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LB21. Preemptive Therapy (PET) vs. Prophylaxis for Prevention of Cytomegalovirus (CMV) Disease in High-Risk Donor Seropositive/Recipient Seronegative (D+R−) Liver Transplant Recipients (LTR): A NIH-Sponsored, Randomized, Controlled, Multicenter Trial

BACKGROUND: Current guidelines preferentially recommend valganciclovir (VGCV) prophylaxis over PET in most D+R− organ transplant populations, but adequately powered direct comparative clinical trials are lacking. METHODS: D+R− LTR were randomly assigned (1:1, stratified by site and T-cell depleting...

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Detalles Bibliográficos
Autores principales: Singh, Nina, Winston, Drew, Razonable, Raymund R, Lyon III, G Marshall, Silveira, Fernanda P, Wagener, Marilyn, Limaye, Ajit P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254092/
http://dx.doi.org/10.1093/ofid/ofy229.2195