Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation

A simple and efficient protocol has been developed for the direct synthesis of γ-nitrobutyric acid methyl esters under microwave irradiation. This methodology reduces reaction times from days to minutes, compared to conventional conditions. Additionally, these conditions increased yields and provide...

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Detalles Bibliográficos
Autores principales: Escalante, Jaime, Díaz-Coutiño, Francisco D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254152/
https://www.ncbi.nlm.nih.gov/pubmed/19384288
http://dx.doi.org/10.3390/molecules14041595
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author Escalante, Jaime
Díaz-Coutiño, Francisco D.
author_facet Escalante, Jaime
Díaz-Coutiño, Francisco D.
author_sort Escalante, Jaime
collection PubMed
description A simple and efficient protocol has been developed for the direct synthesis of γ-nitrobutyric acid methyl esters under microwave irradiation. This methodology reduces reaction times from days to minutes, compared to conventional conditions. Additionally, these conditions increased yields and provided cleaner reactions.
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spelling pubmed-62541522018-11-30 Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation Escalante, Jaime Díaz-Coutiño, Francisco D. Molecules Article A simple and efficient protocol has been developed for the direct synthesis of γ-nitrobutyric acid methyl esters under microwave irradiation. This methodology reduces reaction times from days to minutes, compared to conventional conditions. Additionally, these conditions increased yields and provided cleaner reactions. Molecular Diversity Preservation International (MDPI) 2009-04-21 /pmc/articles/PMC6254152/ /pubmed/19384288 http://dx.doi.org/10.3390/molecules14041595 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Escalante, Jaime
Díaz-Coutiño, Francisco D.
Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation
title Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation
title_full Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation
title_fullStr Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation
title_full_unstemmed Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation
title_short Synthesis of γ-Nitro Aliphatic Methyl Esters Via Michael Additions Promoted by Microwave Irradiation
title_sort synthesis of γ-nitro aliphatic methyl esters via michael additions promoted by microwave irradiation
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254152/
https://www.ncbi.nlm.nih.gov/pubmed/19384288
http://dx.doi.org/10.3390/molecules14041595
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