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1419. 24-Hour Pharmacokinetic Relationships for Intravenous Vancomycin and Novel Urinary Biomarkers of Acute Kidney Injury

BACKGROUND: Vancomycin induces exposure-related acute kidney injury; yet only troughs are generally monitored in patients. In rat models, intraperitoneal dosing results in highly variable drug exposures. Thus, intravenous (IV) vancomycin was used to assess pharmacokinetic-toxicodynamic (PK-TD) relat...

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Detalles Bibliográficos
Autores principales:	Avedissian, Sean, Liu, Jiajun, O’Donnell, J Nicholas, Pais, Gwendolyn, Becher, Leighton, Joshi, Medha, Prozialeck, Walter, Lamar, Peter, Lodise, Thomas P, Scheetz, Marc H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254309/ http://dx.doi.org/10.1093/ofid/ofy210.1250

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