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Depletion of plasma membrane–associated phosphoinositides mimics inhibition of TRPM7 channels by cytosolic Mg(2+), spermine, and pH

Transient receptor potential cation channel subfamily M member 7 (TRPM7) is an ion channel/protein kinase belonging to the TRP melastatin and eEF2 kinase families. Under physiological conditions, most native TRPM7 channels are inhibited by cytoplasmic Mg(2+), protons, and polyamines. Currents throug...

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Detalles Bibliográficos
Autores principales:	Zhelay, Tetyana, Wieczerzak, Krystyna B., Beesetty, Pavani, Alter, Gerald M., Matsushita, Masayuki, Kozak, J. Ashot
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254349/ https://www.ncbi.nlm.nih.gov/pubmed/30305398 http://dx.doi.org/10.1074/jbc.RA118.004066

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