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Functional metagenomics identifies an exosialidase with an inverting catalytic mechanism that defines a new glycoside hydrolase family (GH156)

Exosialidases are glycoside hydrolases that remove a single terminal sialic acid residue from oligosaccharides. They are widely distributed in biology, having been found in prokaryotes, eukaryotes, and certain viruses. Most characterized prokaryotic sialidases are from organisms that are pathogenic...

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Detalles Bibliográficos
Autores principales:	Chuzel, Léa, Ganatra, Mehul B., Rapp, Erdmann, Henrissat, Bernard, Taron, Christopher H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2018
Materias:	Glycobiology and Extracellular Matrices
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254351/ https://www.ncbi.nlm.nih.gov/pubmed/30249617 http://dx.doi.org/10.1074/jbc.RA118.003302

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