Cargando…

Alkylation of 2,4-(1H,3H)-Quinazolinediones with Dialkyl Carbonates Under Microwave Irradiations

Alkylation is a very important chemical reaction which modifies the biological properties of drugs. Quinazolinedione derivatives are of considerable interest due to their wide array of pharmacological properties. We now report application of a practical alkylation procedure to several quinazolinedio...

Descripción completa

Detalles Bibliográficos
Autores principales:	Rivero, Ignacio Alfredo, Guerrero, Leticia, Espinoza, Karla Alejandra, Meza, Martha Cecilia, Rodríguez, Jesús Ramón
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International 2009
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254370/ https://www.ncbi.nlm.nih.gov/pubmed/19471206 http://dx.doi.org/10.3390/molecules14051860

Ejemplares similares

Synthesis of 3-N-Sugar-substituted-2, 4(1H, 3H)-quinazolinediones as Anti-Angiogenesis Agents
por: Huang, Conghai, et al.
Publicado: (2009)

Continuous Flow Alcoholysis of Dialkyl H-Phosphonates with Aliphatic Alcohols
por: Bálint, Erika, et al.
Publicado: (2018)

Mn(III)-Mediated C–H Phosphorylation of Indazoles with Dialkyl Phosphites
por: Ghosh, Payel, et al.
Publicado: (2019)

A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines
por: Nanaji, Yerramsetti, et al.
Publicado: (2020)

New Cycloadditon Reaction of 2-Chloroprop-2-enethioamides with Dialkyl Acetylenedicarboxylates: Synthesis of Dialkyl 2-[4,5-bis(alkoxycarbonyl)-2-(aryl{alkyl}imino)-3(2H)-thienylidene]-1,3-dithiole-4,5-dicarboxylates
por: Ogurtsov, Vladimir A., et al.
Publicado: (2022)

Rational Design and Lead Optimisation of Potent Antimalarial Quinazolinediones and Their Cytotoxicity against MCF-7
por: Charoensutthivarakul, Sitthivut, et al.
Publicado: (2023)

Direct alkylation of N,N-dialkyl benzamides with methyl sulfides under transition metal-free conditions
por: Bao, Can-Can, et al.
Publicado: (2021)

Antitarget Interaction, Acute Toxicity and Protein Binding Studies of Quinazolinedione Sulphonamides as GABA(1) Antagonists
por: Ajeet,, et al.
Publicado: (2016)

Bypassing Fluoroquinolone Resistance with Quinazolinediones: Studies of Drug–Gyrase–DNA Complexes Having Implications for Drug Design
por: Drlica, Karl, et al.
Publicado: (2014)

Microwave-Assisted Saponification Method Followed by Solid-Phase Extraction for the Characterization of Sterols and Dialkyl Ketones in Fats
por: Mascrez, Steven, et al.
Publicado: (2021)

Microwave alkylation of lithium tetrazolate
por: Müller, Danny, et al.
Publicado: (2016)

Dialkyl Carbonates in the Green Synthesis of Heterocycles
por: Tundo, Pietro, et al.
Publicado: (2019)

Reversible N‐Heterocyclic Carbene‐Induced α‐H Abstraction in Tungsten(VI) Imido Dialkyl Dialkoxide Complexes
por: Musso, Janis V., et al.
Publicado: (2020)

Optimization of Potent and Selective Quinazolinediones: Inhibitors of Respiratory Syncytial Virus That Block RNA-Dependent RNA-Polymerase Complex Activity
por: Matharu, Daljit S., et al.
Publicado: (2014)

Dialkyl Ether Formation at High-Valent Nickel
por: Le Vaillant, Franck, et al.
Publicado: (2020)

A Novel One-Pot and One-Step Microwave-Assisted Cyclization-Methylation Reaction of Amino Alcohols and Acetylated Derivatives with Dimethyl Carbonate and TBAC
por: Ochoa-Terán, Adrián, et al.
Publicado: (2014)

Intermolecular dialkylation of alkenes with two distinct C(sp(3))─H bonds enabled by synergistic photoredox catalysis and iron catalysis
por: Ouyang, Xuan-Hui, et al.
Publicado: (2019)

The Effect of Dialkyl Peroxide Crosslinking on the Properties of LLDPE and UHMWPE
por: Cardoso, Pollyana S. M., et al.
Publicado: (2021)

Studies on the Selective Syntheses of Sodium Ditelluride and Dialkyl Ditellurides
por: Kim, Chorong, et al.
Publicado: (2022)

N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation
por: Gianquinto, Eleonora, et al.
Publicado: (2022)

Repositioning of Quinazolinedione-Based Compounds on Soluble Epoxide Hydrolase (sEH) through 3D Structure-Based Pharmacophore Model-Driven Investigation
por: Gazzillo, Erica, et al.
Publicado: (2022)

Simple and Efficient Microwave Assisted N-Alkylation of Isatin
por: Shmidt, María Sol, et al.
Publicado: (2008)

Concentrations of dialkyl phosphate metabolites of organophosphorus pesticides in the U.S. population.
por: Barr, Dana B, et al.
Publicado: (2004)

Dialkylation of Indoles with Trichloroacetimidates to Access 3,3-Disubstituted Indolenines
por: Suzuki, Tamie, et al.
Publicado: (2019)

Re-evaluation of the mechanism of cytotoxicity of dialkylated lariat ether compounds
por: Carrasquel-Ursulaez, Willy, et al.
Publicado: (2020)

An Efficient Method for Selective Syntheses of Sodium Selenide and Dialkyl Selenides
por: Shin, Na Hye, et al.
Publicado: (2022)

A Study of the Bisphosphonic Derivatives from the Pudovik Reaction of Dialkyl α-Oxophosphonates and >P(O)H Reagents: X-ray Structure and Bioactivity
por: Szalai, Zsuzsanna, et al.
Publicado: (2023)

CuSO(4)/H(2)O(2)-Catalyzed Lignin Depolymerization under the Irradiation of Microwaves
por: Dai, Jinhuo, et al.
Publicado: (2018)

General Allylic C–H Alkylation with Tertiary Nucleophiles
por: Howell, Jennifer M., et al.
Publicado: (2014)

Alcohols as alkylating agents in heteroarene C–H functionalization
por: Jin, Jian, et al.
Publicado: (2015)

Photoinduced iron-catalyzed C–H alkylation of polyolefins
por: Zhang, Zongnan, et al.
Publicado: (2023)

Weak Base-Promoted Lactamization under Microwave Irradiation: Synthesis of Quinolin-2(1H)-ones and Phenanthridin-6(5H)-ones
por: Dao, Pham Duy Quang, et al.
Publicado: (2018)

Synthesis and Properties of N-Bromosuccinimide Derivatives of Ammonium Dialkyl/Alkylene Dithiophosphates
por: Harkut, Neelam, et al.
Publicado: (2007)

Directed nickel-catalyzed 1,2-dialkylation of alkenyl carbonyl compounds
por: Derosa, Joseph, et al.
Publicado: (2018)

Optimization and a Kinetic Study on the Acidic Hydrolysis of Dialkyl α-Hydroxybenzylphosphonates
por: Harsági, Nikoletta, et al.
Publicado: (2020)

Dialkyl Succinates and Adipates as Alternative Plasticizers—Even More Efficient Synthesis
por: Barteczko, Natalia, et al.
Publicado: (2021)

Efficient Synthesis of Acylated, Dialkyl α-Hydroxy-Benzylphosphonates and Their Anticancer Activity
por: Varga, Petra R., et al.
Publicado: (2022)

Molecular diversity of the base-promoted reaction of phenacylmalononitriles with dialkyl but-2-ynedioates
por: Zheng, Hui, et al.
Publicado: (2022)

Assessment of DNA Topoisomerase I Unwinding Activity, Radical Scavenging Capacity, and Inhibition of Breast Cancer Cell Viability of N-alkyl-acridones and N,N′-dialkyl-9,9′-biacridylidenes
por: Krokidis, Marios G., et al.
Publicado: (2019)

Smelting of Scandium by Microwave Irradiation
por: Fujii, Satoshi, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_q1aivdtg6du0mrf5nv357c0av9