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Effective Targeting of TAG72(+) Peritoneal Ovarian Tumors via Regional Delivery of CAR-Engineered T Cells

Impressive clinical efficacy of chimeric antigen receptor (CAR)-engineered T cell therapy for hematological malignancies have prompted significant efforts in achieving similar responses in solid tumors. The lack of truly restricted and uniform expression of tumor-associated antigens, as well as limi...

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Detalles Bibliográficos
Autores principales:	Murad, John P., Kozlowska, Anna K., Lee, Hee Jun, Ramamurthy, Maya, Chang, Wen-Chung, Yazaki, Paul, Colcher, David, Shively, John, Cristea, Mihaela, Forman, Stephen J., Priceman, Saul J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254427/ https://www.ncbi.nlm.nih.gov/pubmed/30510550 http://dx.doi.org/10.3389/fimmu.2018.02268

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