Cargando…

2015. Host Gene Expression Identifies Infectious Triggers of Asthma Exacerbation

BACKGROUND: Asthma exacerbations often occur due to infectious triggers. However, determining whether an infection is present and whether it is bacterial or viral remains clinically challenging leading to antibiotic overuse. A diagnostic strategy that clarifies these uncertainties can enable persona...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lydon, Emily, Bullard, Charles, Aydin, Mert, Better, Olga, Mazur, Anna, Mcclain, Micah T, Ginsburg, Geoffrey S, Woods, Christopher W, Burke, Thomas, Henao, Ricardo, Tsalik, Ephraim L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254466/ http://dx.doi.org/10.1093/ofid/ofy210.1671

Ejemplares similares

A host gene expression approach for identifying triggers of asthma exacerbations
por: Lydon, Emily C., et al.
Publicado: (2019)

2014. TLDA Validation of a Host Response Signature to Discriminate Bacterial, Viral, and Non-infectious Causes of Illness
por: Lydon, Emily, et al.
Publicado: (2018)

2012. FilmArray(®) Measurement of Host Response Signatures RapidLy Discriminates Viral, Bacterial, and Non-infectious Etiologies of Illness
por: Tsalik, Ephraim L, et al.
Publicado: (2018)

1330. Evaluation of Multiple Host Response-Based Strategies to Classify Acute Respiratory Illness
por: Ross, Melissa H, et al.
Publicado: (2019)

A comparison of host response strategies to distinguish bacterial and viral infection
por: Ross, Melissa, et al.
Publicado: (2021)

Systematic comparison of published host gene expression signatures for bacterial/viral discrimination
por: Bodkin, Nicholas, et al.
Publicado: (2022)

305. PBMC-Derived Transcriptomic Signatures Accurately Discriminate Between Viral, Bacterial, and Fungal Infections and can be Translated to Real-World Human Infections
por: Steinbrink, Julie M, et al.
Publicado: (2023)

1226. Performance of a Host Response Test for Bacterial/Viral Discrimination in Immunocompromised Patients
por: Mahle, Rachael E, et al.
Publicado: (2020)

2595. Murine Models for the Host Response to Typical and Atypical Pneumonia
por: Khan, Kirin, et al.
Publicado: (2019)

1218. Comparing the Diagnostic Accuracy of Clinician Judgement to a Novel Host Response Diagnostic for Acute Respiratory Illness
por: Jaffe, Ian S, et al.
Publicado: (2020)

A miRNA Host Response Signature Accurately Discriminates Acute Respiratory Infection Etiologies
por: Poore, Gregory D., et al.
Publicado: (2018)

Validation of a host response test to distinguish bacterial and viral respiratory infection
por: Lydon, Emily C., et al.
Publicado: (2019)

The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches
por: Steinbrink, Julie M., et al.
Publicado: (2021)

A blood-based host gene expression assay for early detection of respiratory viral infection: an index-cluster prospective cohort study
por: McClain, Micah T, et al.
Publicado: (2021)

2018. Host Gene Expression Classifiers Distinguish Bacterial and Viral Infections in Sri Lankan Patients with Acute Febrile Respiratory Illness
por: Gayani Tillekeratne, L, et al.
Publicado: (2018)

Assessment of the Feasibility of Using Noninvasive Wearable Biometric Monitoring Sensors to Detect Influenza and the Common Cold Before Symptom Onset
por: Grzesiak, Emilia, et al.
Publicado: (2021)

Pilot study of myocardial ischemia-induced metabolomic changes in emergency department patients undergoing stress testing
por: Limkakeng, Alexander T., et al.
Publicado: (2019)

Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection
por: Burke, Thomas W., et al.
Publicado: (2017)

Dysregulated transcriptional responses to SARS-CoV-2 in the periphery support novel diagnostic approaches
por: McClain, Micah T., et al.
Publicado: (2020)

Previously Derived Host Gene Expression Classifiers Identify Bacterial and Viral Etiologies of Acute Febrile Respiratory Illness in a South Asian Population
por: Tillekeratne, L Gayani, et al.
Publicado: (2020)

An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility
por: Wang, Liuyang, et al.
Publicado: (2020)

An atlas connecting shared genetic architecture of human diseases and molecular phenotypes provides insight into COVID-19 susceptibility
por: Wang, Liuyang, et al.
Publicado: (2021)

The Host Response to Viral Infections Reveals Common and Virus-Specific Signatures in the Peripheral Blood
por: Tsalik, Ephraim L., et al.
Publicado: (2021)

2885. A Host Transcriptional Signature for Accurate Diagnosis of Candidemia in the Hospital Setting
por: Steinbrink, Julie M, et al.
Publicado: (2019)

A Genomic Signature of Influenza Infection Shows Potential for Presymptomatic Detection, Guiding Early Therapy, and Monitoring Clinical Responses
por: McClain, Micah T., et al.
Publicado: (2016)

Infectious triggers of asthma
por: MacDowell, Ana L., et al.
Publicado: (2005)

Dysregulated transcriptional responses to SARS-CoV-2 in the periphery
por: McClain, Micah T., et al.
Publicado: (2021)

A Decade On: Systematic Review of ClinicalTrials.gov Infectious Disease Trials, 2007–2017
por: Jaffe, Ian S, et al.
Publicado: (2019)

Blood RNA alternative splicing events as diagnostic biomarkers for infectious disease
por: Zhang, Zijun, et al.
Publicado: (2023)

Chromatin remodeling in peripheral blood cells reflects COVID-19 symptom severity
por: Giroux, Nicholas S., et al.
Publicado: (2020)

Viewing both sides of the coin for infectious disease diagnosis
por: Strouts, Fiona R., et al.
Publicado: (2023)

SARS‐CoV‐2 reinfection across a spectrum of immunological states
por: McKittrick, Justine M., et al.
Publicado: (2022)

1216. Benchmarking Published Gene Signatures for Robust Infection Classification
por: Bodkin, Nicholas, et al.
Publicado: (2020)

A crowdsourced analysis to identify ab initio molecular signatures predictive of susceptibility to viral infection
por: Fourati, Slim, et al.
Publicado: (2018)

Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion
por: Giroux, Nicholas S., et al.
Publicado: (2022)

Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion
por: Giroux, Nicholas S., et al.
Publicado: (2022)

Author Correction: Differential chromatin accessibility in peripheral blood mononuclear cells underlies COVID-19 disease severity prior to seroconversion
por: Giroux, Nicholas S., et al.
Publicado: (2023)

Is respiratory viral infection really an important trigger of asthma exacerbations in children?
por: Lee, So-lun, et al.
Publicado: (2011)

Acute Asthma in the Pediatric Emergency Department: Infections Are the Main Triggers of Exacerbations
por: Dondi, Arianna, et al.
Publicado: (2017)

The State of Infectious Diseases Clinical Trials: A Systematic Review of ClinicalTrials.gov
por: Goswami, Neela D., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_sb6eopito1q2phbaj57qiqekj1