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In vivo analysis of outer arm dynein transport reveals cargo-specific intraflagellar transport properties

Outer dynein arms (ODAs) are multiprotein complexes that drive flagellar beating. Based on genetic and biochemical analyses, ODAs preassemble in the cell body and then move into the flagellum by intraflagellar transport (IFT). To study ODA transport in vivo, we expressed the essential intermediate c...

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Detalles Bibliográficos
Autores principales: Dai, Jin, Barbieri, Francesco, Mitchell, David R., Lechtreck, Karl F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254574/
https://www.ncbi.nlm.nih.gov/pubmed/30133350
http://dx.doi.org/10.1091/mbc.E18-05-0291