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Cell cycle localization dynamics of mitochondrial DNA polymerase IC in African trypanosomes

Trypanosoma brucei has a unique catenated mitochondrial DNA (mtDNA) network called kinetoplast DNA (kDNA). Replication of kDNA occurs once per cell cycle in near synchrony with nuclear S phase and requires the coordination of many proteins. Among these are three essential DNA polymerases (TbPOLIB, I...

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Detalles Bibliográficos
Autores principales: Concepción-Acevedo, Jeniffer, Miller, Jonathan C., Boucher, Michael J., Klingbeil, Michele M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254582/
https://www.ncbi.nlm.nih.gov/pubmed/30133333
http://dx.doi.org/10.1091/mbc.E18-02-0127