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Clinical factors predicting drug-induced liver injury due to flucloxacillin

OBJECTIVES: Drug-induced liver injury (DILI) is a serious adverse reaction due to flucloxacillin. The pathogenesis is not fully understood. Female sex, age over 60 years, and a longer treatment duration have been suggested to be predisposing factors. Carriers of HLA-B*57:01 have an 80-fold increased...

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Detalles Bibliográficos
Autores principales:	Lindh, Mikaela, Hallberg, Pär, Yue, Qun-Ying, Wadelius, Mia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254585/ https://www.ncbi.nlm.nih.gov/pubmed/30538582 http://dx.doi.org/10.2147/DHPS.S178394

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