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Successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report

OBJECTIVE: This paper reports on a rare case of pregnancy after uterine artery embolization (UAE) for uterine arteriovenous malformation (AVM). Debate exists about persistence of fertility in women after UAE. Adverse effects of this technique can modify both uterine echostructure, inducing necrosis...

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Autores principales: Guida, M, Maffucci, D, Iannuzzi, G, Giordano, M, Luciano, G, Di Benedetto, L, Cantarella, R, Rescigno, A, Giugliano, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254590/
https://www.ncbi.nlm.nih.gov/pubmed/30538584
http://dx.doi.org/10.2147/IJWH.S182131
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author Guida, M
Maffucci, D
Iannuzzi, G
Giordano, M
Luciano, G
Di Benedetto, L
Cantarella, R
Rescigno, A
Giugliano, L
author_facet Guida, M
Maffucci, D
Iannuzzi, G
Giordano, M
Luciano, G
Di Benedetto, L
Cantarella, R
Rescigno, A
Giugliano, L
author_sort Guida, M
collection PubMed
description OBJECTIVE: This paper reports on a rare case of pregnancy after uterine artery embolization (UAE) for uterine arteriovenous malformation (AVM). Debate exists about persistence of fertility in women after UAE. Adverse effects of this technique can modify both uterine echostructure, inducing necrosis and infarction, endometrial atrophy and uterine artery rupture, and ovarian reserve, causing persistent amenorrhea. Ovarian reserve appears to be affected by UAE in pre-menopausal women. However, younger ovaries (according to biological ovarian age) exhibit a greater capacity for recovery after ovarian damage. Therefore, larger studies are needed for more conclusive results. CASE REPORT: A 28-year-old woman was admitted to our department due to life-threatening uterine bleeding, resulting in tachycardia, pallor, and sweating. The patient came with a history of two spontaneous miscarriages. After sonography and computed tomography, AVMs were identified at uterine fundus and anterior wall. CONCLUSION: The pathogenesis of infertility after UAE is not yet known. The peculiarity of this case was that, only few months later, the patient became pregnant and gave birth to a live fetus at 37 weeks with cesarean delivery.
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spelling pubmed-62545902018-12-11 Successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report Guida, M Maffucci, D Iannuzzi, G Giordano, M Luciano, G Di Benedetto, L Cantarella, R Rescigno, A Giugliano, L Int J Womens Health Case Report OBJECTIVE: This paper reports on a rare case of pregnancy after uterine artery embolization (UAE) for uterine arteriovenous malformation (AVM). Debate exists about persistence of fertility in women after UAE. Adverse effects of this technique can modify both uterine echostructure, inducing necrosis and infarction, endometrial atrophy and uterine artery rupture, and ovarian reserve, causing persistent amenorrhea. Ovarian reserve appears to be affected by UAE in pre-menopausal women. However, younger ovaries (according to biological ovarian age) exhibit a greater capacity for recovery after ovarian damage. Therefore, larger studies are needed for more conclusive results. CASE REPORT: A 28-year-old woman was admitted to our department due to life-threatening uterine bleeding, resulting in tachycardia, pallor, and sweating. The patient came with a history of two spontaneous miscarriages. After sonography and computed tomography, AVMs were identified at uterine fundus and anterior wall. CONCLUSION: The pathogenesis of infertility after UAE is not yet known. The peculiarity of this case was that, only few months later, the patient became pregnant and gave birth to a live fetus at 37 weeks with cesarean delivery. Dove Medical Press 2018-11-21 /pmc/articles/PMC6254590/ /pubmed/30538584 http://dx.doi.org/10.2147/IJWH.S182131 Text en © 2018 Guida et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Case Report
Guida, M
Maffucci, D
Iannuzzi, G
Giordano, M
Luciano, G
Di Benedetto, L
Cantarella, R
Rescigno, A
Giugliano, L
Successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report
title Successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report
title_full Successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report
title_fullStr Successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report
title_full_unstemmed Successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report
title_short Successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report
title_sort successful pregnancy after uterine artery embolization for uterine arterovenous malformation: a rare case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254590/
https://www.ncbi.nlm.nih.gov/pubmed/30538584
http://dx.doi.org/10.2147/IJWH.S182131
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