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2201. Prevalence of Hepatitis C in Adults Presenting to Emergency Departments in a Large Hospital System in Texas

BACKGROUND: Hepatitis C is a chronic life-threatening disease which is curable. However, ~60% of Hep C-infected individuals are unaware of their infection status. The majority of Hep C has been documented in baby boomers (born 1946–1965; PMID:22895429). METHODS: Prospective case study of adults pres...

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Autores principales: Prater, Samuel, Rodriguez, Gilhen, Green, Pam, Heresi, Gloria P, Murphy, James R, McCarthy, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254600/
http://dx.doi.org/10.1093/ofid/ofy210.1854
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author Prater, Samuel
Rodriguez, Gilhen
Green, Pam
Heresi, Gloria P
Murphy, James R
McCarthy, James
author_facet Prater, Samuel
Rodriguez, Gilhen
Green, Pam
Heresi, Gloria P
Murphy, James R
McCarthy, James
author_sort Prater, Samuel
collection PubMed
description BACKGROUND: Hepatitis C is a chronic life-threatening disease which is curable. However, ~60% of Hep C-infected individuals are unaware of their infection status. The majority of Hep C has been documented in baby boomers (born 1946–1965; PMID:22895429). METHODS: Prospective case study of adults presenting to the Emergency Departments (EDs) of a large is not for profit hospital system in the Houston, Texas area. Adults presenting between March 2013 and October 2016 were eligible for testing for antibody to Hep C (Gilead). RESULTS: Over the 3.5 years study, 8,159 patients presenting to nine participating EDs in the Houston, Texas region were screened for Hep C. There were 744 (10.0%) individuals found positive. Prevalence of Hep C by testing ED ranged from 4.0 to 13.7% (P < 0.001) and males (11.8%) were significantly (P < 0.001) more frequently positive than females (6.6%). When parsed by age categories; individuals born before 1946 (3.8% Hep C positive) had a significantly lower (P < 0.001) prevalence of Hep C than cohorts born between 1946 and 1965 (9.6%+) or after 1965 (9.2%+). CONCLUSION: Hep C is prevalent in adult patients presenting to EDs in the Houston, Texas region. The 10% Hep C positivity rate is similar to that found (11.6%) in another Gulf state, Alabama (PMID: 26611776). Our findings differ in that prevalence in individuals born after 1965 was as high as that for baby boomers. DISCLOSURES: J. McCarthy, Gilead: Research Contractor, Research support.
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spelling pubmed-62546002018-11-28 2201. Prevalence of Hepatitis C in Adults Presenting to Emergency Departments in a Large Hospital System in Texas Prater, Samuel Rodriguez, Gilhen Green, Pam Heresi, Gloria P Murphy, James R McCarthy, James Open Forum Infect Dis Abstracts BACKGROUND: Hepatitis C is a chronic life-threatening disease which is curable. However, ~60% of Hep C-infected individuals are unaware of their infection status. The majority of Hep C has been documented in baby boomers (born 1946–1965; PMID:22895429). METHODS: Prospective case study of adults presenting to the Emergency Departments (EDs) of a large is not for profit hospital system in the Houston, Texas area. Adults presenting between March 2013 and October 2016 were eligible for testing for antibody to Hep C (Gilead). RESULTS: Over the 3.5 years study, 8,159 patients presenting to nine participating EDs in the Houston, Texas region were screened for Hep C. There were 744 (10.0%) individuals found positive. Prevalence of Hep C by testing ED ranged from 4.0 to 13.7% (P < 0.001) and males (11.8%) were significantly (P < 0.001) more frequently positive than females (6.6%). When parsed by age categories; individuals born before 1946 (3.8% Hep C positive) had a significantly lower (P < 0.001) prevalence of Hep C than cohorts born between 1946 and 1965 (9.6%+) or after 1965 (9.2%+). CONCLUSION: Hep C is prevalent in adult patients presenting to EDs in the Houston, Texas region. The 10% Hep C positivity rate is similar to that found (11.6%) in another Gulf state, Alabama (PMID: 26611776). Our findings differ in that prevalence in individuals born after 1965 was as high as that for baby boomers. DISCLOSURES: J. McCarthy, Gilead: Research Contractor, Research support. Oxford University Press 2018-11-26 /pmc/articles/PMC6254600/ http://dx.doi.org/10.1093/ofid/ofy210.1854 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Abstracts
Prater, Samuel
Rodriguez, Gilhen
Green, Pam
Heresi, Gloria P
Murphy, James R
McCarthy, James
2201. Prevalence of Hepatitis C in Adults Presenting to Emergency Departments in a Large Hospital System in Texas
title 2201. Prevalence of Hepatitis C in Adults Presenting to Emergency Departments in a Large Hospital System in Texas
title_full 2201. Prevalence of Hepatitis C in Adults Presenting to Emergency Departments in a Large Hospital System in Texas
title_fullStr 2201. Prevalence of Hepatitis C in Adults Presenting to Emergency Departments in a Large Hospital System in Texas
title_full_unstemmed 2201. Prevalence of Hepatitis C in Adults Presenting to Emergency Departments in a Large Hospital System in Texas
title_short 2201. Prevalence of Hepatitis C in Adults Presenting to Emergency Departments in a Large Hospital System in Texas
title_sort 2201. prevalence of hepatitis c in adults presenting to emergency departments in a large hospital system in texas
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254600/
http://dx.doi.org/10.1093/ofid/ofy210.1854
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