Cargando…

1915. Predicting Real-Time Risk of Complications in the Postoperative Setting With Temperature as a Single Variable

BACKGROUND: No real-time postoperative risk stratification model exists to predict complications following surgery. The aim of this work is to understand if we can successfully risk stratify patients across three distinct surgeries using group-based trajectory modeling (GBTM) with only a single vari...

Descripción completa

Detalles Bibliográficos
Autores principales: Kaplar, Katherine, Ravichandran, Urmila, Parikh, Ronak, Bhaimia, Eric, Baied, Elias, Lahrman, Frances, Saeed, Huma, Paruch, Jennifer, Padman, Rema, Shah, Nirav, Grant, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254610/
http://dx.doi.org/10.1093/ofid/ofy210.1571
_version_ 1783373760747798528
author Kaplar, Katherine
Ravichandran, Urmila
Parikh, Ronak
Bhaimia, Eric
Baied, Elias
Lahrman, Frances
Saeed, Huma
Paruch, Jennifer
Padman, Rema
Shah, Nirav
Grant, Jennifer
author_facet Kaplar, Katherine
Ravichandran, Urmila
Parikh, Ronak
Bhaimia, Eric
Baied, Elias
Lahrman, Frances
Saeed, Huma
Paruch, Jennifer
Padman, Rema
Shah, Nirav
Grant, Jennifer
author_sort Kaplar, Katherine
collection PubMed
description BACKGROUND: No real-time postoperative risk stratification model exists to predict complications following surgery. The aim of this work is to understand if we can successfully risk stratify patients across three distinct surgeries using group-based trajectory modeling (GBTM) with only a single variable, temperature. METHODS: We performed a retrospective study of adults undergoing elective total knee arthroplasty (TKA), total hip arthroplasty (THA), colectomy, and pancreatectomy at an academic medical center from October 2014 to February 2018. Clinical data were abstracted using definitions from the National Surgical Quality Improvement Program (NSQIP) and temperature data were extracted from the Database Warehouse. GBTM was used to identify distinct clusters of patients with similar temperature trajectories. We calculated rates of complications and combined all NSQIP infectious and inflammatory complications into a single metric hence forth labeled inflammatory complications. Chi-square test was used to compare categorical variables. RESULTS: We identified 815 independent surgical patients: 307 TKA/THA, 195 pancreatectomy, and 313 colectomy patients. Rates of all NSQIP complications were 1.6% for TKA/THA, 35.4% for pancreatectomy and 10.2% for colectomy at 30 days after surgery. Pancreatectomy patients clustered into two temperature trajectories and both TKA/THA and colectomy patients (Figure 1) clustered into three groups. Inflammatory complication frequencies were significantly different in colectomy and trended toward significance for TKA/THA and pancreatectomy (Table 1). CONCLUSION: Temperature trajectory modeling may help identify postoperative patients at higher risk for surgical complication after surgery. While risk stratification seems to work better in high complication surgeries or models with more patients, the promise of this modeling technique relies on the ability to identify high-risk patients with a single variable. DISCLOSURES: All authors: No reported disclosures.
format Online
Article
Text
id pubmed-6254610
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-62546102018-11-28 1915. Predicting Real-Time Risk of Complications in the Postoperative Setting With Temperature as a Single Variable Kaplar, Katherine Ravichandran, Urmila Parikh, Ronak Bhaimia, Eric Baied, Elias Lahrman, Frances Saeed, Huma Paruch, Jennifer Padman, Rema Shah, Nirav Grant, Jennifer Open Forum Infect Dis Abstracts BACKGROUND: No real-time postoperative risk stratification model exists to predict complications following surgery. The aim of this work is to understand if we can successfully risk stratify patients across three distinct surgeries using group-based trajectory modeling (GBTM) with only a single variable, temperature. METHODS: We performed a retrospective study of adults undergoing elective total knee arthroplasty (TKA), total hip arthroplasty (THA), colectomy, and pancreatectomy at an academic medical center from October 2014 to February 2018. Clinical data were abstracted using definitions from the National Surgical Quality Improvement Program (NSQIP) and temperature data were extracted from the Database Warehouse. GBTM was used to identify distinct clusters of patients with similar temperature trajectories. We calculated rates of complications and combined all NSQIP infectious and inflammatory complications into a single metric hence forth labeled inflammatory complications. Chi-square test was used to compare categorical variables. RESULTS: We identified 815 independent surgical patients: 307 TKA/THA, 195 pancreatectomy, and 313 colectomy patients. Rates of all NSQIP complications were 1.6% for TKA/THA, 35.4% for pancreatectomy and 10.2% for colectomy at 30 days after surgery. Pancreatectomy patients clustered into two temperature trajectories and both TKA/THA and colectomy patients (Figure 1) clustered into three groups. Inflammatory complication frequencies were significantly different in colectomy and trended toward significance for TKA/THA and pancreatectomy (Table 1). CONCLUSION: Temperature trajectory modeling may help identify postoperative patients at higher risk for surgical complication after surgery. While risk stratification seems to work better in high complication surgeries or models with more patients, the promise of this modeling technique relies on the ability to identify high-risk patients with a single variable. DISCLOSURES: All authors: No reported disclosures. Oxford University Press 2018-11-26 /pmc/articles/PMC6254610/ http://dx.doi.org/10.1093/ofid/ofy210.1571 Text en © The Author(s) 2018. Published by Oxford University Press on behalf of Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Abstracts
Kaplar, Katherine
Ravichandran, Urmila
Parikh, Ronak
Bhaimia, Eric
Baied, Elias
Lahrman, Frances
Saeed, Huma
Paruch, Jennifer
Padman, Rema
Shah, Nirav
Grant, Jennifer
1915. Predicting Real-Time Risk of Complications in the Postoperative Setting With Temperature as a Single Variable
title 1915. Predicting Real-Time Risk of Complications in the Postoperative Setting With Temperature as a Single Variable
title_full 1915. Predicting Real-Time Risk of Complications in the Postoperative Setting With Temperature as a Single Variable
title_fullStr 1915. Predicting Real-Time Risk of Complications in the Postoperative Setting With Temperature as a Single Variable
title_full_unstemmed 1915. Predicting Real-Time Risk of Complications in the Postoperative Setting With Temperature as a Single Variable
title_short 1915. Predicting Real-Time Risk of Complications in the Postoperative Setting With Temperature as a Single Variable
title_sort 1915. predicting real-time risk of complications in the postoperative setting with temperature as a single variable
topic Abstracts
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254610/
http://dx.doi.org/10.1093/ofid/ofy210.1571
work_keys_str_mv AT kaplarkatherine 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT ravichandranurmila 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT parikhronak 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT bhaimiaeric 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT baiedelias 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT lahrmanfrances 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT saeedhuma 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT paruchjennifer 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT padmanrema 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT shahnirav 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable
AT grantjennifer 1915predictingrealtimeriskofcomplicationsinthepostoperativesettingwithtemperatureasasinglevariable