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MERIT40-dependent recruitment of tankyrase to damaged DNA and its implication for cell sensitivity to DNA-damaging anticancer drugs

Tankyrase, a member of the poly(ADP-ribose) polymerase (PARP) family, regulates various intracellular responses, such as telomere maintenance, Wnt/β-catenin signaling and cell cycle progression through its interactions with multiple target proteins. Tankyrase contains a long stretch of 24 ankyrin re...

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Detalles Bibliográficos
Autores principales: Okamoto, Keiji, Ohishi, Tomokazu, Kuroiwa, Mika, Iemura, Shun-ichiro, Natsume, Tohru, Seimiya, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254674/
https://www.ncbi.nlm.nih.gov/pubmed/30533199
http://dx.doi.org/10.18632/oncotarget.26312

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