Coupling Reactions of α-Bromocarboxylate with Non-Aromatic N-Heterocycles ‡

The conditions for the C-N bond forming reaction (C-N coupling reaction) between α-bromocarboxylate and nitrogen-containing non-aromatic heterocyclic rings under heterogeneous copper(I) oxide catalysis are investigated in this paper. All the generated compounds were fully characterized by IR, NMR an...

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Detalles Bibliográficos
Autores principales: Brychtova, Katerina, Slaba, Barbora, Placek, Lukas, Jampilek, Josef, Raich, Ivan, Csollei, Jozef
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254713/
https://www.ncbi.nlm.nih.gov/pubmed/19701142
http://dx.doi.org/10.3390/molecules14083019
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author Brychtova, Katerina
Slaba, Barbora
Placek, Lukas
Jampilek, Josef
Raich, Ivan
Csollei, Jozef
author_facet Brychtova, Katerina
Slaba, Barbora
Placek, Lukas
Jampilek, Josef
Raich, Ivan
Csollei, Jozef
author_sort Brychtova, Katerina
collection PubMed
description The conditions for the C-N bond forming reaction (C-N coupling reaction) between α-bromocarboxylate and nitrogen-containing non-aromatic heterocyclic rings under heterogeneous copper(I) oxide catalysis are investigated in this paper. All the generated compounds were fully characterized by IR, NMR and MS spectroscopy. Ab initio/DFT calculations of partial charges on nitrogen atoms in all the discussed heterocycles and on C((2)) of carboxylate under applied conditions were predicted. These in silico results correlate relatively with the experimental observations.
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spelling pubmed-62547132018-11-30 Coupling Reactions of α-Bromocarboxylate with Non-Aromatic N-Heterocycles ‡ Brychtova, Katerina Slaba, Barbora Placek, Lukas Jampilek, Josef Raich, Ivan Csollei, Jozef Molecules Article The conditions for the C-N bond forming reaction (C-N coupling reaction) between α-bromocarboxylate and nitrogen-containing non-aromatic heterocyclic rings under heterogeneous copper(I) oxide catalysis are investigated in this paper. All the generated compounds were fully characterized by IR, NMR and MS spectroscopy. Ab initio/DFT calculations of partial charges on nitrogen atoms in all the discussed heterocycles and on C((2)) of carboxylate under applied conditions were predicted. These in silico results correlate relatively with the experimental observations. Molecular Diversity Preservation International 2009-08-13 /pmc/articles/PMC6254713/ /pubmed/19701142 http://dx.doi.org/10.3390/molecules14083019 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Brychtova, Katerina
Slaba, Barbora
Placek, Lukas
Jampilek, Josef
Raich, Ivan
Csollei, Jozef
Coupling Reactions of α-Bromocarboxylate with Non-Aromatic N-Heterocycles ‡
title Coupling Reactions of α-Bromocarboxylate with Non-Aromatic N-Heterocycles ‡
title_full Coupling Reactions of α-Bromocarboxylate with Non-Aromatic N-Heterocycles ‡
title_fullStr Coupling Reactions of α-Bromocarboxylate with Non-Aromatic N-Heterocycles ‡
title_full_unstemmed Coupling Reactions of α-Bromocarboxylate with Non-Aromatic N-Heterocycles ‡
title_short Coupling Reactions of α-Bromocarboxylate with Non-Aromatic N-Heterocycles ‡
title_sort coupling reactions of α-bromocarboxylate with non-aromatic n-heterocycles ‡
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254713/
https://www.ncbi.nlm.nih.gov/pubmed/19701142
http://dx.doi.org/10.3390/molecules14083019
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