Synthesis and Antimicrobial Activity of Some Pyridinium Salts

Some substituted benzylidenehydrazinylpyridinium derivatives bearing benzyl, ethylphenyl and propylphenyl groups on the pyridinium nitrogen were synthesized and screened for possible antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and C...

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Autores principales: Alptüzün, Vildan, Parlar, Sülünay, Taşlı, Hüseyin, Erciyas, Ercin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254721/
https://www.ncbi.nlm.nih.gov/pubmed/20032886
http://dx.doi.org/10.3390/molecules14125203
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author Alptüzün, Vildan
Parlar, Sülünay
Taşlı, Hüseyin
Erciyas, Ercin
author_facet Alptüzün, Vildan
Parlar, Sülünay
Taşlı, Hüseyin
Erciyas, Ercin
author_sort Alptüzün, Vildan
collection PubMed
description Some substituted benzylidenehydrazinylpyridinium derivatives bearing benzyl, ethylphenyl and propylphenyl groups on the pyridinium nitrogen were synthesized and screened for possible antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans using the microdilution method. Antimicrobial test results indicated that compounds containing a 3-phenylpropyl chain displayed the highest antimicrobial activity against Staphylococcus aureus and the compound 3d was the most active in the series against all tested bacteria and fungi strains.
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spelling pubmed-62547212018-11-30 Synthesis and Antimicrobial Activity of Some Pyridinium Salts Alptüzün, Vildan Parlar, Sülünay Taşlı, Hüseyin Erciyas, Ercin Molecules Article Some substituted benzylidenehydrazinylpyridinium derivatives bearing benzyl, ethylphenyl and propylphenyl groups on the pyridinium nitrogen were synthesized and screened for possible antibacterial and antifungal activities against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Candida albicans using the microdilution method. Antimicrobial test results indicated that compounds containing a 3-phenylpropyl chain displayed the highest antimicrobial activity against Staphylococcus aureus and the compound 3d was the most active in the series against all tested bacteria and fungi strains. Molecular Diversity Preservation International 2009-12-14 /pmc/articles/PMC6254721/ /pubmed/20032886 http://dx.doi.org/10.3390/molecules14125203 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Alptüzün, Vildan
Parlar, Sülünay
Taşlı, Hüseyin
Erciyas, Ercin
Synthesis and Antimicrobial Activity of Some Pyridinium Salts
title Synthesis and Antimicrobial Activity of Some Pyridinium Salts
title_full Synthesis and Antimicrobial Activity of Some Pyridinium Salts
title_fullStr Synthesis and Antimicrobial Activity of Some Pyridinium Salts
title_full_unstemmed Synthesis and Antimicrobial Activity of Some Pyridinium Salts
title_short Synthesis and Antimicrobial Activity of Some Pyridinium Salts
title_sort synthesis and antimicrobial activity of some pyridinium salts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254721/
https://www.ncbi.nlm.nih.gov/pubmed/20032886
http://dx.doi.org/10.3390/molecules14125203
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AT erciyasercin synthesisandantimicrobialactivityofsomepyridiniumsalts

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