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Synthesis and Anti-Human Immunodeficiency Virus Type 1 Activity of (E)-N-Phenylstyryl-N-alkylacetamide Derivatives

A series of (E)-N-phenylstyryl-N-alkylacetamides, 5, were synthesized by direct reduction-acetylation of β-arylnitroolefins, followed by N-alkylation. The title compounds were characterized by (1)H-NMR, EIMS and IR analysis. All the synthesized compounds were assayed as HIV-1 non-nucleoside reverse...

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Detalles Bibliográficos
Autores principales: Cheng, Pi, Chen, Ji-Jun, Huang, Ning, Wang, Rui-Rui, Zheng, Yong-Tang, Liang, Yi-Zeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254728/
https://www.ncbi.nlm.nih.gov/pubmed/19783916
http://dx.doi.org/10.3390/molecules14093176