703. Mechanisms of High-Level Ceftolozane/Tazobactam (CT) Resistance Against Pseudomonas aeruginosa and Synergy Between CT and Tobramycin (TOB)

BACKGROUND: Ceftolozane/tazobactam (CT) is a cephalosporin/β-lactamase inhibitor with excellent activity against multi-drug-resistant (MDR) P. aeruginosa (PSA). Several cases of CT-resistance (CT-R) development after exposure have been reported. We recovered a PSA isolate with high-level CT-R from a...

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Detalles Bibliográficos
Autores principales: So, Wonhee, Shurko, James, Galega, Ralph, Quilitz, Rod E, Greene, John, Lee, Grace C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
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Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254764/
http://dx.doi.org/10.1093/ofid/ofy210.710

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