Low-Density Lipoprotein-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice

BACKGROUND: Atherosclerotic cardiovascular disease is a chronic inflammatory process initiated when cholesterol-carrying low-density lipoprotein (LDL) is retained in the arterial wall. CD4(+) T cells, some of which recognize peptide components of LDL as antigen, are recruited to the forming lesion,...

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Detalles Bibliográficos
Autores principales: Gisterå, Anton, Klement, Maria L., Polyzos, Konstantinos A., Mailer, Reiner K.W., Duhlin, Amanda, Karlsson, Mikael C.I., Ketelhuth, Daniel F.J., Hansson, Göran K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2018
Materias:
Original Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254780/
https://www.ncbi.nlm.nih.gov/pubmed/29997115
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254780/
https://www.ncbi.nlm.nih.gov/pubmed/29997115
http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034076

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