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Low-Density Lipoprotein-Reactive T Cells Regulate Plasma Cholesterol Levels and Development of Atherosclerosis in Humanized Hypercholesterolemic Mice

BACKGROUND: Atherosclerotic cardiovascular disease is a chronic inflammatory process initiated when cholesterol-carrying low-density lipoprotein (LDL) is retained in the arterial wall. CD4(+) T cells, some of which recognize peptide components of LDL as antigen, are recruited to the forming lesion,...

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Detalles Bibliográficos
Autores principales:	Gisterå, Anton, Klement, Maria L., Polyzos, Konstantinos A., Mailer, Reiner K.W., Duhlin, Amanda, Karlsson, Mikael C.I., Ketelhuth, Daniel F.J., Hansson, Göran K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2018
Materias:	Original Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254780/ https://www.ncbi.nlm.nih.gov/pubmed/29997115 http://dx.doi.org/10.1161/CIRCULATIONAHA.118.034076

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