1970. Phase 1 Clinical Trial of Intranasal Immunization with M2-Deficient, Single Replication, Live Influenza Vaccine (M2SR): Safety and Immune Response in Adults

BACKGROUND: Influenza vaccines are needed with greater effectiveness and breadth of coverage. FluGen is developing M2SR (M2 deficient Single Replication), an investigational, live virus vaccine. M2SR contains the internal proteins of donor A/Puerto Rico/8/34 and hemagglutinin (HA) and neuraminidase...

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Detalles Bibliográficos
Autores principales: Eiden, Joseph, Gordon, Gilad, Fierro, Carlos, Belshe, Robert, Greenberg, Harry, Hoft, Dan, Hatta, Yasuko, Imboden, Michael, Moser, Mike, Herber, Renee, Boltz, David, Tary-Lehmann, Magdalena, Kawaoka, Yoshihiro, Neumann, Gabriele, Radspinner, Paul, Aitchison, Roger, Bilsel, Pamuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254821/
http://dx.doi.org/10.1093/ofid/ofy210.1626

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