Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst

The Brønsted acid ionic liquid [PyN(CH(2))(4)SO(3)H][p-CH(3)PhSO(3)] has been reported as an efficient catalyst for the Michael addition reaction of indoles to α,β-unsaturated ketones. Satisfactory results were obtained, with excellent yields and a simple experimental procedure. The catalyst could b...

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Detalles Bibliográficos
Autores principales: Yu, Chuan-Ji, Liu, Chen-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254839/
https://www.ncbi.nlm.nih.gov/pubmed/19783920
http://dx.doi.org/10.3390/molecules14093222
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author Yu, Chuan-Ji
Liu, Chen-Jiang
author_facet Yu, Chuan-Ji
Liu, Chen-Jiang
author_sort Yu, Chuan-Ji
collection PubMed
description The Brønsted acid ionic liquid [PyN(CH(2))(4)SO(3)H][p-CH(3)PhSO(3)] has been reported as an efficient catalyst for the Michael addition reaction of indoles to α,β-unsaturated ketones. Satisfactory results were obtained, with excellent yields and a simple experimental procedure. The catalyst could be recycled and reused up to three times without any noticeable decrease in the catalytic activity.
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spelling pubmed-62548392018-11-30 Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst Yu, Chuan-Ji Liu, Chen-Jiang Molecules Article The Brønsted acid ionic liquid [PyN(CH(2))(4)SO(3)H][p-CH(3)PhSO(3)] has been reported as an efficient catalyst for the Michael addition reaction of indoles to α,β-unsaturated ketones. Satisfactory results were obtained, with excellent yields and a simple experimental procedure. The catalyst could be recycled and reused up to three times without any noticeable decrease in the catalytic activity. Molecular Diversity Preservation International 2009-08-27 /pmc/articles/PMC6254839/ /pubmed/19783920 http://dx.doi.org/10.3390/molecules14093222 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Yu, Chuan-Ji
Liu, Chen-Jiang
Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst
title Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst
title_full Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst
title_fullStr Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst
title_full_unstemmed Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst
title_short Conjugate Addition of Indoles to α,β-Unsaturated Ketones Using a Brønsted Acid Ionic Liquid as an Efficient Catalyst
title_sort conjugate addition of indoles to α,β-unsaturated ketones using a brønsted acid ionic liquid as an efficient catalyst
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254839/
https://www.ncbi.nlm.nih.gov/pubmed/19783920
http://dx.doi.org/10.3390/molecules14093222
work_keys_str_mv AT yuchuanji conjugateadditionofindolestoabunsaturatedketonesusingabrønstedacidionicliquidasanefficientcatalyst
AT liuchenjiang conjugateadditionofindolestoabunsaturatedketonesusingabrønstedacidionicliquidasanefficientcatalyst

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