Long non-coding RNA HOTAIR mediates the switching of histone H3 lysine 27 acetylation to methylation to promote epithelial-to-mesenchymal transition in gastric cancer

HOX transcript antisense intergenic RNA (HOTAIR), a well-known long non-coding RNA, plays an important role in the regulation of epithelial-to-mesenchymal transition (EMT). In this study, we propose a novel mechanism through which HOTAIR promotes EMT by switching histone H3 lysine 27 acetylation to...

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Detalles Bibliográficos
Autores principales: Song, Yue, Wang, Rui, Li, Li-Wei, Liu, Xi, Wang, Yun-Fei, Wang, Qi-Xue, Zhang, Qingyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254860/
https://www.ncbi.nlm.nih.gov/pubmed/30431069
http://dx.doi.org/10.3892/ijo.2018.4625

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