Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media

A highly efficient palladium acetate-catalyzed ligand-free Suzuki reaction of 2,3,5-trichloropyridine with arylboronic acids in aqueous phase was developed. High yields of 3,5-dichloro-2-arylpyridines, a simple Pd source, absence of ligands, and environmentally benign as well as mild reaction condit...

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Autores principales: Hu, Huanan, Ge, Changhua, Zhang, Anjiang, Ding, Lisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254914/
https://www.ncbi.nlm.nih.gov/pubmed/19783914
http://dx.doi.org/10.3390/molecules14093153
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author Hu, Huanan
Ge, Changhua
Zhang, Anjiang
Ding, Lisheng
author_facet Hu, Huanan
Ge, Changhua
Zhang, Anjiang
Ding, Lisheng
author_sort Hu, Huanan
collection PubMed
description A highly efficient palladium acetate-catalyzed ligand-free Suzuki reaction of 2,3,5-trichloropyridine with arylboronic acids in aqueous phase was developed. High yields of 3,5-dichloro-2-arylpyridines, a simple Pd source, absence of ligands, and environmentally benign as well as mild reaction conditions are important features of this method.
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spelling pubmed-62549142018-11-30 Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media Hu, Huanan Ge, Changhua Zhang, Anjiang Ding, Lisheng Molecules Article A highly efficient palladium acetate-catalyzed ligand-free Suzuki reaction of 2,3,5-trichloropyridine with arylboronic acids in aqueous phase was developed. High yields of 3,5-dichloro-2-arylpyridines, a simple Pd source, absence of ligands, and environmentally benign as well as mild reaction conditions are important features of this method. Molecular Diversity Preservation International 2009-08-26 /pmc/articles/PMC6254914/ /pubmed/19783914 http://dx.doi.org/10.3390/molecules14093153 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Hu, Huanan
Ge, Changhua
Zhang, Anjiang
Ding, Lisheng
Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media
title Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media
title_full Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media
title_fullStr Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media
title_full_unstemmed Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media
title_short Synthesis of Novel 3,5-Dichloro-2-arylpyridines by Palladium Acetate-Catalyzed Ligand-Free Suzuki Reactions in Aqueous Media
title_sort synthesis of novel 3,5-dichloro-2-arylpyridines by palladium acetate-catalyzed ligand-free suzuki reactions in aqueous media
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254914/
https://www.ncbi.nlm.nih.gov/pubmed/19783914
http://dx.doi.org/10.3390/molecules14093153
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AT zhanganjiang synthesisofnovel35dichloro2arylpyridinesbypalladiumacetatecatalyzedligandfreesuzukireactionsinaqueousmedia
AT dinglisheng synthesisofnovel35dichloro2arylpyridinesbypalladiumacetatecatalyzedligandfreesuzukireactionsinaqueousmedia

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