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Sphingosine kinase 1 promotes the metastasis of colorectal cancer by inducing the epithelial-mesenchymal transition mediated by the FAK/AKT/MMPs axis

It was demonstrated that Sphingosine kinase 1 (SphK1) promotes tumor progression and confers the malignancy phenotype of colorectal cancer by activating the focal adhesion kinase (FAK) pathway. However, further clarification is required to determine if SphK1 promotes the metastasis of colorectal can...

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Detalles Bibliográficos
Autores principales:	Liu, Shi-Quan, Xu, Chun-Yan, Wu, Wen-Hong, Fu, Zhen-Hua, He, Si-Wei, Qin, Meng-Bin, Huang, Jie-An
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254930/ https://www.ncbi.nlm.nih.gov/pubmed/30365116 http://dx.doi.org/10.3892/ijo.2018.4607

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