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A New Look at the Most Successful Prodrugs for Active Vitamin D (D Hormone): Alfacalcidol and Doxercalciferol
Alfacalcidol (1α-hydroxyvitamin D(3)) has been widely used since 1981 as a prodrug for calcitriol (1α,25-dihydroxyvitamin D(3)) in the treatment of hypocalcemia, chronic renal failure, hypoparathyroidism and osteoporosis. More recently, doxercalciferol (1α-hydroxyvitamin D(2)) has been used since 19...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Molecular Diversity Preservation International
2009
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254965/ https://www.ncbi.nlm.nih.gov/pubmed/19924035 http://dx.doi.org/10.3390/molecules14103869 |