Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives

New imidazole ring derivatives comprising 1,3-oxazoline, Schiff's bases, thiadiazole, oxadiazole and 1,2,4-triazole moieties are reported. 3-Aminobiimidazol-4-one compounds 7a-c were synthesized by the reaction of compounds 6a-c with hydrazine hydrate. Biimidazole esters 9a-c were converted int...

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Autor principal: Atia, Abdul Jabar Kh.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254976/
https://www.ncbi.nlm.nih.gov/pubmed/19633614
http://dx.doi.org/10.3390/molecules14072431
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author Atia, Abdul Jabar Kh.
author_facet Atia, Abdul Jabar Kh.
author_sort Atia, Abdul Jabar Kh.
collection PubMed
description New imidazole ring derivatives comprising 1,3-oxazoline, Schiff's bases, thiadiazole, oxadiazole and 1,2,4-triazole moieties are reported. 3-Aminobiimidazol-4-one compounds 7a-c were synthesized by the reaction of compounds 6a-c with hydrazine hydrate. Biimidazole esters 9a-c were converted into biimidazole hydrazide esters 10a-c. Compounds 7a-c and 10a-c were converted into a variety of derivatives.
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spelling pubmed-62549762018-11-30 Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives Atia, Abdul Jabar Kh. Molecules Article New imidazole ring derivatives comprising 1,3-oxazoline, Schiff's bases, thiadiazole, oxadiazole and 1,2,4-triazole moieties are reported. 3-Aminobiimidazol-4-one compounds 7a-c were synthesized by the reaction of compounds 6a-c with hydrazine hydrate. Biimidazole esters 9a-c were converted into biimidazole hydrazide esters 10a-c. Compounds 7a-c and 10a-c were converted into a variety of derivatives. Molecular Diversity Preservation International 2009-07-08 /pmc/articles/PMC6254976/ /pubmed/19633614 http://dx.doi.org/10.3390/molecules14072431 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Atia, Abdul Jabar Kh.
Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives
title Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives
title_full Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives
title_fullStr Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives
title_full_unstemmed Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives
title_short Synthesis and Antibacterial Activities of New Metronidazole and Imidazole Derivatives
title_sort synthesis and antibacterial activities of new metronidazole and imidazole derivatives
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254976/
https://www.ncbi.nlm.nih.gov/pubmed/19633614
http://dx.doi.org/10.3390/molecules14072431
work_keys_str_mv AT atiaabduljabarkh synthesisandantibacterialactivitiesofnewmetronidazoleandimidazolederivatives

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