Synthesis and Antitumor Activity of Amino Acid Ester Derivatives Containing 5-Fluorouracil

A series of amino acid ester derivatives containing 5-fluorouracil were synthesized using 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC·HCl) and N-hydroxybenzotriazole (HOBt) as a coupling agent. The structures of the products were assigned by NMR, MS, IR etc. The in vitro antitum...

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Detalles Bibliográficos
Autores principales: Xiong, Jing, Zhu, Hai-Feng, Zhao, Ya-Juan, Lan, Yun-Jun, Jiang, Ji-Wang, Yang, Jing-Jing, Zhang, Shu-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254981/
https://www.ncbi.nlm.nih.gov/pubmed/19783913
http://dx.doi.org/10.3390/molecules14093142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6254981/
https://www.ncbi.nlm.nih.gov/pubmed/19783913
http://dx.doi.org/10.3390/molecules14093142

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