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2395. Mechanism-Based-Susceptibility Testing (MBST) Using Disc Diffusion Assays (DDA) to Guide Treatment of Multidrug- and Extensively Drug-Resistant Pseudomonas aeruginosa (MDR-XDR-Pa) in a Cystic Fibrosis (CF) Lung Transplant Recipient; Are We Ready for Combination Therapy vs. MDR-XDR-Pa?
BACKGROUND: Lung infections with MDR-XDR-Pa in patients with CF are challenging due to the emergence of antibiotic resistance. We applied MBST with DDA to guide combination antibiotic therapy in an 18-year-old woman with CF. We investigated if this approach can assist in choosing effective regimens....
Autores principales: | Abbo, Lilian M, Yasmin, Mohamad, Marshall, Steven H, Perez, Federico, Corzo-Pedrosa, Mónica, Camargo, Jose F, Simkins, Jacques, Aragon, Laura, Anjan, Shweta, Morris, Michele I, Brozzi, Nicolas, Loebe, Mathias, Fulmer, Jesse, Sinha, Neeraj, Martinez, Octavio, Perez-Cardona, Armando, Colin, Andrew, Cloke, Christina, Bonomo, Robert A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255010/ http://dx.doi.org/10.1093/ofid/ofy210.2048 |
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