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639. Indoleamine 2,3 Dioxygenase, Age, and Chronic Immune Activation in HIV Patients
BACKGROUND: Immune activation complicates HIV despite antiretroviral therapy (ART). Indoleamine 2,3 dioxygenase (IDO) catabolizes tryptophan (T) to kynurenine (K), regulating immune activity. IDO activity increases in HIV patients and non-HIV patients with age. This study examines the relationship o...
Autores principales: | Baer, Stephanie, Colombo, Rhonda, Johnson, Maribeth, Wakade, Sushama, Pacholczyk, Gabriela, Thompson, Stuart, Huang, Lei, Saag, Michael, Mellor, Andrew |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255015/ http://dx.doi.org/10.1093/ofid/ofy210.646 |
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