A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO(2)

Structurally diverse thiazoles with electron-donating and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO(2)) oxidation of the corresponding thiazolines. The effect of substitution at the 2- and 4-positions was investigated. The desired thiazoles with aryl or...

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Detalles Bibliográficos
Autores principales: Yu, Yan-Bo, Chen, Hong-Liang, Wang, Li-Yi, Chen, Xin-Zheng, Fu, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255030/
https://www.ncbi.nlm.nih.gov/pubmed/20032864
http://dx.doi.org/10.3390/molecules14124858
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author Yu, Yan-Bo
Chen, Hong-Liang
Wang, Li-Yi
Chen, Xin-Zheng
Fu, Bin
author_facet Yu, Yan-Bo
Chen, Hong-Liang
Wang, Li-Yi
Chen, Xin-Zheng
Fu, Bin
author_sort Yu, Yan-Bo
collection PubMed
description Structurally diverse thiazoles with electron-donating and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO(2)) oxidation of the corresponding thiazolines. The effect of substitution at the 2- and 4-positions was investigated. The desired thiazoles with aryl or vinyl substitutions at the 2- or 4-position can be obtained in good to excellent yields.
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spelling pubmed-62550302018-11-30 A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO(2) Yu, Yan-Bo Chen, Hong-Liang Wang, Li-Yi Chen, Xin-Zheng Fu, Bin Molecules Communication Structurally diverse thiazoles with electron-donating and electron-withdrawing groups were conveniently synthesized through manganese dioxide (MnO(2)) oxidation of the corresponding thiazolines. The effect of substitution at the 2- and 4-positions was investigated. The desired thiazoles with aryl or vinyl substitutions at the 2- or 4-position can be obtained in good to excellent yields. Molecular Diversity Preservation International 2009-11-26 /pmc/articles/PMC6255030/ /pubmed/20032864 http://dx.doi.org/10.3390/molecules14124858 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Yu, Yan-Bo
Chen, Hong-Liang
Wang, Li-Yi
Chen, Xin-Zheng
Fu, Bin
A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO(2)
title A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO(2)
title_full A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO(2)
title_fullStr A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO(2)
title_full_unstemmed A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO(2)
title_short A Facile Synthesis of 2,4-Disubstituted Thiazoles Using MnO(2)
title_sort facile synthesis of 2,4-disubstituted thiazoles using mno(2)
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255030/
https://www.ncbi.nlm.nih.gov/pubmed/20032864
http://dx.doi.org/10.3390/molecules14124858
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