Depigmenting Effect of Catechins

The aim of the present work was to clarify the anti-melanogenic mechanism of the catechin group. In this study, we used (-)-epigallocatechin-3-gallate (EGCG), (-)-epigallocatechin (EGC), (-)-catechin (C), and gallic acid (GA). The catechin group inhibited melanin synthesis in B16 melanoma cells. To...

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Detalles Bibliográficos
Autores principales: Sato, Kazuomi, Toriyama, Masaru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255032/
https://www.ncbi.nlm.nih.gov/pubmed/19924076
http://dx.doi.org/10.3390/molecules14114425
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author Sato, Kazuomi
Toriyama, Masaru
author_facet Sato, Kazuomi
Toriyama, Masaru
author_sort Sato, Kazuomi
collection PubMed
description The aim of the present work was to clarify the anti-melanogenic mechanism of the catechin group. In this study, we used (-)-epigallocatechin-3-gallate (EGCG), (-)-epigallocatechin (EGC), (-)-catechin (C), and gallic acid (GA). The catechin group inhibited melanin synthesis in B16 melanoma cells. To elucidate the anti-melanogenic mechanism of the catechin group, we performed Western blotting analysis for crucial melanogenic protein, namely tyrosinase. The catechin group inhibited tyrosinase expression. These results indicate that the catechin group is a candidate anti-melanogenic agent and that it might be effective in hyperpigmentation disorders.
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spelling pubmed-62550322018-11-30 Depigmenting Effect of Catechins Sato, Kazuomi Toriyama, Masaru Molecules Communication The aim of the present work was to clarify the anti-melanogenic mechanism of the catechin group. In this study, we used (-)-epigallocatechin-3-gallate (EGCG), (-)-epigallocatechin (EGC), (-)-catechin (C), and gallic acid (GA). The catechin group inhibited melanin synthesis in B16 melanoma cells. To elucidate the anti-melanogenic mechanism of the catechin group, we performed Western blotting analysis for crucial melanogenic protein, namely tyrosinase. The catechin group inhibited tyrosinase expression. These results indicate that the catechin group is a candidate anti-melanogenic agent and that it might be effective in hyperpigmentation disorders. Molecular Diversity Preservation International 2009-11-04 /pmc/articles/PMC6255032/ /pubmed/19924076 http://dx.doi.org/10.3390/molecules14114425 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Communication
Sato, Kazuomi
Toriyama, Masaru
Depigmenting Effect of Catechins
title Depigmenting Effect of Catechins
title_full Depigmenting Effect of Catechins
title_fullStr Depigmenting Effect of Catechins
title_full_unstemmed Depigmenting Effect of Catechins
title_short Depigmenting Effect of Catechins
title_sort depigmenting effect of catechins
topic Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255032/
https://www.ncbi.nlm.nih.gov/pubmed/19924076
http://dx.doi.org/10.3390/molecules14114425
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