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644. How Antibody Isotype Affects Anti-Capsular Antibody Protection Against Carbapenem-Resistant Klebsiella pneumoniae Infection
BACKGROUND: New monoclonal antibodies (mAb) are being developed against infectious disease. However, antibody isotype is an important consideration, as different IgG variants interact with different Fc receptors and differ in avidity due to Fc structural differences. Our recent anti-capsular murine...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255079/ http://dx.doi.org/10.1093/ofid/ofy210.651 |