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644. How Antibody Isotype Affects Anti-Capsular Antibody Protection Against Carbapenem-Resistant Klebsiella pneumoniae Infection

BACKGROUND: New monoclonal antibodies (mAb) are being developed against infectious disease. However, antibody isotype is an important consideration, as different IgG variants interact with different Fc receptors and differ in avidity due to Fc structural differences. Our recent anti-capsular murine...

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Detalles Bibliográficos
Autores principales:	Motley, Michael, Diago-Navarro, Elizabeth, Fries, Bettina C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255079/ http://dx.doi.org/10.1093/ofid/ofy210.651

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