Amides from Piper capense with CNS Activity – A Preliminary SAR Analysis

Piper capense L.f. (Piperaceae) is used traditionally in South Africa as a sleep inducing remedy. Bioassay-guided fractionation of the roots of P. capense led to the isolation of piperine (1) and 4,5-dihydropiperine (2), which showed moderate affinity for the benzodiazepine site on the GABA(A) recep...

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Detalles Bibliográficos
Autores principales: Pedersen, Mikael E., Metzler, Bjørn, Stafford, Gary I., van Staden, Johannes, Jäger, Anna K., Rasmussen, Hasse B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255099/
https://www.ncbi.nlm.nih.gov/pubmed/19783959
http://dx.doi.org/10.3390/molecules14093833

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255099/
https://www.ncbi.nlm.nih.gov/pubmed/19783959
http://dx.doi.org/10.3390/molecules14093833

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