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Quantifying resilience of humans and other animals

All life requires the capacity to recover from challenges that are as inevitable as they are unpredictable. Understanding this resilience is essential for managing the health of humans and their livestock. It has long been difficult to quantify resilience directly, forcing practitioners to rely on i...

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Detalles Bibliográficos
Autores principales: Scheffer, Marten, Bolhuis, J. Elizabeth, Borsboom, Denny, Buchman, Timothy G., Gijzel, Sanne M. W., Goulson, Dave, Kammenga, Jan E., Kemp, Bas, van de Leemput, Ingrid A., Levin, Simon, Martin, Carmel Mary, Melis, René J. F., van Nes, Egbert H., Romero, L. Michael, Olde Rikkert, Marcel G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255191/
https://www.ncbi.nlm.nih.gov/pubmed/30373844
http://dx.doi.org/10.1073/pnas.1810630115
Descripción
Sumario:All life requires the capacity to recover from challenges that are as inevitable as they are unpredictable. Understanding this resilience is essential for managing the health of humans and their livestock. It has long been difficult to quantify resilience directly, forcing practitioners to rely on indirect static indicators of health. However, measurements from wearable electronics and other sources now allow us to analyze the dynamics of physiology and behavior with unsurpassed resolution. The resulting flood of data coincides with the emergence of novel analytical tools for estimating resilience from the pattern of microrecoveries observed in natural time series. Such dynamic indicators of resilience may be used to monitor the risk of systemic failure across systems ranging from organs to entire organisms. These tools invite a fundamental rethinking of our approach to the adaptive management of health and resilience.