Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis

One new drimane-type sesquiterpenoid, named ugandenial A (1), was isolated from the ethyl acetate extract of the bark of Warburgia ugandensis (Canellaceae) together with eight known drimane-type sesquiterpenoids: 11α-hydroxycinnamosmolide (2), warburganal (3), polygodial (4), mukaadial (5), dendocar...

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Autores principales: Xu, Min, Litaudon, Marc, Krief, Sabrina, Martin, Marie-Thérèse, Kasenene, John, Kiremire, Bernard, Dumontet, Vincent, Guéritte, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255255/
https://www.ncbi.nlm.nih.gov/pubmed/19924033
http://dx.doi.org/10.3390/molecules14103844
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author Xu, Min
Litaudon, Marc
Krief, Sabrina
Martin, Marie-Thérèse
Kasenene, John
Kiremire, Bernard
Dumontet, Vincent
Guéritte, Françoise
author_facet Xu, Min
Litaudon, Marc
Krief, Sabrina
Martin, Marie-Thérèse
Kasenene, John
Kiremire, Bernard
Dumontet, Vincent
Guéritte, Françoise
author_sort Xu, Min
collection PubMed
description One new drimane-type sesquiterpenoid, named ugandenial A (1), was isolated from the ethyl acetate extract of the bark of Warburgia ugandensis (Canellaceae) together with eight known drimane-type sesquiterpenoids: 11α-hydroxycinnamosmolide (2), warburganal (3), polygodial (4), mukaadial (5), dendocarbin A (6), 9α-hydroxycinnamolide (7), dendocarbin L (8) and dendocarbin M (9). Their structures were established by detailed spectroscopic analysis. In addition a keto-enol equilibrium was demonstrated for compound 1 through a detailed NMR analysis run in CD(2)Cl(2) at 190 K. Cytotoxicity of the isolated compounds against KB cells was evaluated.
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spelling pubmed-62552552018-11-30 Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis Xu, Min Litaudon, Marc Krief, Sabrina Martin, Marie-Thérèse Kasenene, John Kiremire, Bernard Dumontet, Vincent Guéritte, Françoise Molecules Article One new drimane-type sesquiterpenoid, named ugandenial A (1), was isolated from the ethyl acetate extract of the bark of Warburgia ugandensis (Canellaceae) together with eight known drimane-type sesquiterpenoids: 11α-hydroxycinnamosmolide (2), warburganal (3), polygodial (4), mukaadial (5), dendocarbin A (6), 9α-hydroxycinnamolide (7), dendocarbin L (8) and dendocarbin M (9). Their structures were established by detailed spectroscopic analysis. In addition a keto-enol equilibrium was demonstrated for compound 1 through a detailed NMR analysis run in CD(2)Cl(2) at 190 K. Cytotoxicity of the isolated compounds against KB cells was evaluated. Molecular Diversity Preservation International 2009-09-28 /pmc/articles/PMC6255255/ /pubmed/19924033 http://dx.doi.org/10.3390/molecules14103844 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Xu, Min
Litaudon, Marc
Krief, Sabrina
Martin, Marie-Thérèse
Kasenene, John
Kiremire, Bernard
Dumontet, Vincent
Guéritte, Françoise
Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis
title Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis
title_full Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis
title_fullStr Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis
title_full_unstemmed Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis
title_short Ugandenial A, a New Drimane-type Sesquiterpenoid from Warburgia ugandensis
title_sort ugandenial a, a new drimane-type sesquiterpenoid from warburgia ugandensis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255255/
https://www.ncbi.nlm.nih.gov/pubmed/19924033
http://dx.doi.org/10.3390/molecules14103844
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