A New Friedelane Type Triterpene from Euonymus hederaceus

Euonymus hederaceus is distributed widely in the south of China; its stems and leaves have been used as folk medicines to treat many diseases such as renal deficiency and chronic diarrhea, traumatic injury, and abnormal menstruation. Chemical investigation of the leaves and stems of Euonymus hederaceus resulted in the isolation for the first time and characterization of a new friedelane type triterpene with a molecular mass of 472 and molecular formula of C(30)H(48)O(4) by high resolution mass spectrometry. The (1)H-NMR (13)C-NMR and DEPT135(0) spectra matched the characteristic data of the proposed triterpene skeleton. The compound was finally identified as 28-hydroxyfriedelan-3-one-29-oic acid on the basis of spectroscopic evidence, including two dimensional nuclear magnetic resonance as well as its IR spectrum.