Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species

X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the dihydrokaempferol crystals were collected on a CAD4...

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Detalles Bibliográficos
Autores principales: Redzynia, Izabela, Ziółkowska, Natasza E., Majzner, Wiesław R., Willför, Stefan, Sjöholm, Rainer, Eklund, Patrik, Bujacz, Grzegorz D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255330/
https://www.ncbi.nlm.nih.gov/pubmed/19924053
http://dx.doi.org/10.3390/molecules14104147
Descripción
Sumario:X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the dihydrokaempferol crystals were collected on a CAD4 diffractometer and on a synchrotron for the lariciresinol crystal. The investigated compounds inhibit lipid peroxidation and lariciresinol is additionally a good scavenger of superoxide radicals. The structural data presented in this work provide a useful basis for designing more active compounds with potential use as antioxidants.

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