Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species

X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the dihydrokaempferol crystals were collected on a CAD4...

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Autores principales: Redzynia, Izabela, Ziółkowska, Natasza E., Majzner, Wiesław R., Willför, Stefan, Sjöholm, Rainer, Eklund, Patrik, Bujacz, Grzegorz D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255330/
https://www.ncbi.nlm.nih.gov/pubmed/19924053
http://dx.doi.org/10.3390/molecules14104147
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author Redzynia, Izabela
Ziółkowska, Natasza E.
Majzner, Wiesław R.
Willför, Stefan
Sjöholm, Rainer
Eklund, Patrik
Bujacz, Grzegorz D.
author_facet Redzynia, Izabela
Ziółkowska, Natasza E.
Majzner, Wiesław R.
Willför, Stefan
Sjöholm, Rainer
Eklund, Patrik
Bujacz, Grzegorz D.
author_sort Redzynia, Izabela
collection PubMed
description X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the dihydrokaempferol crystals were collected on a CAD4 diffractometer and on a synchrotron for the lariciresinol crystal. The investigated compounds inhibit lipid peroxidation and lariciresinol is additionally a good scavenger of superoxide radicals. The structural data presented in this work provide a useful basis for designing more active compounds with potential use as antioxidants.
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spelling pubmed-62553302018-11-30 Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species Redzynia, Izabela Ziółkowska, Natasza E. Majzner, Wiesław R. Willför, Stefan Sjöholm, Rainer Eklund, Patrik Bujacz, Grzegorz D. Molecules Article X-ray structures of two compounds isolated from wood knots of coniferous trees, namely dihydrokaempferol (3,5,8,13-tetrahydroxyflavanon) and lariciresinol (3,14-dimetoxy-7,10-epoxylignan-4,15,19-triol), are presented here. Diffraction data for the dihydrokaempferol crystals were collected on a CAD4 diffractometer and on a synchrotron for the lariciresinol crystal. The investigated compounds inhibit lipid peroxidation and lariciresinol is additionally a good scavenger of superoxide radicals. The structural data presented in this work provide a useful basis for designing more active compounds with potential use as antioxidants. Molecular Diversity Preservation International 2009-10-16 /pmc/articles/PMC6255330/ /pubmed/19924053 http://dx.doi.org/10.3390/molecules14104147 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Redzynia, Izabela
Ziółkowska, Natasza E.
Majzner, Wiesław R.
Willför, Stefan
Sjöholm, Rainer
Eklund, Patrik
Bujacz, Grzegorz D.
Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species
title Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species
title_full Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species
title_fullStr Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species
title_full_unstemmed Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species
title_short Structural Investigation of Biologically Active Phenolic Compounds Isolated from European Tree Species
title_sort structural investigation of biologically active phenolic compounds isolated from european tree species
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255330/
https://www.ncbi.nlm.nih.gov/pubmed/19924053
http://dx.doi.org/10.3390/molecules14104147
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