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Calpain Inhibition Reduces Axolemmal Leakage in Traumatic Axonal Injury

Calcium-induced, calpain-mediated proteolysis (CMSP) has recently been implicated to the pathogenesis of diffuse (traumatic) axonal injury (TAI). Some studies suggested that subaxolemmal CMSP may contribute to axolemmal permeability (AP) alterations observed in TAI. Seeking direct evidence for this...

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Detalles Bibliográficos
Autores principales: Czeiter, Endre, Büki, András, Bukovics, Péter, Farkas, Orsolya, Pál, József, Kövesdi, Erzsébet, Dóczi, Tamás, Sándor, János
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255382/
https://www.ncbi.nlm.nih.gov/pubmed/20032879
http://dx.doi.org/10.3390/molecules14125115

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