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Microbial Growth and Quorum Sensing Antagonist Activities of Herbal Plants Extracts

Antimicrobial and antiquorum sensing (AQS) activities of fourteen ethanolic extracts of different parts of eight plants were screened against four Gram-positive, five Gram-negative bacteria and four fungi. Depending on the plant part extract used and the test microorganism, variable activities were...

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Autores principales: Al-Hussaini, Reema, Mahasneh, Adel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255472/
https://www.ncbi.nlm.nih.gov/pubmed/19783935
http://dx.doi.org/10.3390/molecules14093425
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author Al-Hussaini, Reema
Mahasneh, Adel M.
author_facet Al-Hussaini, Reema
Mahasneh, Adel M.
author_sort Al-Hussaini, Reema
collection PubMed
description Antimicrobial and antiquorum sensing (AQS) activities of fourteen ethanolic extracts of different parts of eight plants were screened against four Gram-positive, five Gram-negative bacteria and four fungi. Depending on the plant part extract used and the test microorganism, variable activities were recorded at 3 mg per disc. Among the Gram-positive bacteria tested, for example, activities of Laurus nobilis bark extract ranged between a 9.5 mm inhibition zone against Bacillus subtilis up to a 25 mm one against methicillin resistant Staphylococcus aureus. Staphylococcus aureus and Aspergillus fumigatus were the most susceptible among bacteria and fungi tested towards other plant parts. Of interest is the tangible antifungal activity of a Tecoma capensis flower extract, which is reported for the first time. However, minimum inhibitory concentrations (MIC's) for both bacteria and fungi were relatively high (0.5-3.0 mg). As for antiquorum sensing activity against Chromobacterium violaceum, superior activity (>17 mm QS inhibition) was associated with Sonchus oleraceus and Laurus nobilis extracts and weak to good activity (8-17 mm) was recorded for other plants. In conclusion, results indicate the potential of these plant extracts in treating microbial infections through cell growth inhibition or quorum sensing antagonism, which is reported for the first time, thus validating their medicinal use.
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spelling pubmed-62554722018-11-30 Microbial Growth and Quorum Sensing Antagonist Activities of Herbal Plants Extracts Al-Hussaini, Reema Mahasneh, Adel M. Molecules Article Antimicrobial and antiquorum sensing (AQS) activities of fourteen ethanolic extracts of different parts of eight plants were screened against four Gram-positive, five Gram-negative bacteria and four fungi. Depending on the plant part extract used and the test microorganism, variable activities were recorded at 3 mg per disc. Among the Gram-positive bacteria tested, for example, activities of Laurus nobilis bark extract ranged between a 9.5 mm inhibition zone against Bacillus subtilis up to a 25 mm one against methicillin resistant Staphylococcus aureus. Staphylococcus aureus and Aspergillus fumigatus were the most susceptible among bacteria and fungi tested towards other plant parts. Of interest is the tangible antifungal activity of a Tecoma capensis flower extract, which is reported for the first time. However, minimum inhibitory concentrations (MIC's) for both bacteria and fungi were relatively high (0.5-3.0 mg). As for antiquorum sensing activity against Chromobacterium violaceum, superior activity (>17 mm QS inhibition) was associated with Sonchus oleraceus and Laurus nobilis extracts and weak to good activity (8-17 mm) was recorded for other plants. In conclusion, results indicate the potential of these plant extracts in treating microbial infections through cell growth inhibition or quorum sensing antagonism, which is reported for the first time, thus validating their medicinal use. Molecular Diversity Preservation International 2009-09-03 /pmc/articles/PMC6255472/ /pubmed/19783935 http://dx.doi.org/10.3390/molecules14093425 Text en © 2009 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
spellingShingle Article
Al-Hussaini, Reema
Mahasneh, Adel M.
Microbial Growth and Quorum Sensing Antagonist Activities of Herbal Plants Extracts
title Microbial Growth and Quorum Sensing Antagonist Activities of Herbal Plants Extracts
title_full Microbial Growth and Quorum Sensing Antagonist Activities of Herbal Plants Extracts
title_fullStr Microbial Growth and Quorum Sensing Antagonist Activities of Herbal Plants Extracts
title_full_unstemmed Microbial Growth and Quorum Sensing Antagonist Activities of Herbal Plants Extracts
title_short Microbial Growth and Quorum Sensing Antagonist Activities of Herbal Plants Extracts
title_sort microbial growth and quorum sensing antagonist activities of herbal plants extracts
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255472/
https://www.ncbi.nlm.nih.gov/pubmed/19783935
http://dx.doi.org/10.3390/molecules14093425
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