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641. Development of Structural Epitope Targeting During B-cell Ontogeny by Exploration of Relatives of Gp41 Structural Epitope Binding Antibody 6F5

BACKGROUND: In previous studies, our lab has characterized a number of highly mutated antibodies against structural epitopes of the human immunodeficiency virus (HIV) envelope protein. These antibodies were first isolated from long-term nonprogressors (LTNPs). We have previous mapped 6F5 to a novel...

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Detalles Bibliográficos
Autores principales:	Baron, Sarah, Sojar, Hakimuddin, Hoffman, Jonathon, Hicar, Mark
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2018
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255538/ http://dx.doi.org/10.1093/ofid/ofy210.648

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