621. Treatment of Recurrent Clostridium difficile Infection with SER-109 Increases the Concentration of Secondary Bile Acids in a Dose-Dependent Manner

BACKGROUND: C. difficile recurs when dormant spores germinate in the dysbiotic gut, facilitated by an increase of 1° vs. 2° bile acids. SER-109, an ecology of bacterial spores purified from stool of healthy donors, is an investigational first-in-class microbiome therapeutic intended to facilitate mi...

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Detalles Bibliográficos
Autores principales: Henn, Matthew, Ford, Christopher, O’Brien, Edward, Wortman, Jennifer, Diao, Liyang, Desjardins, Christopher, Tomlinson, Amelia, Litcofsky, Kevin, Wilcox, Mark, Buckley, Anthony, Bernardo, Patricia, McGovern, Barbara, Aunins, John G, Cook, David N, Trucksis, Michele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255561/
http://dx.doi.org/10.1093/ofid/ofy210.628

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