IL-4-dependent Jagged1 expression/processing is associated with survival of chronic lymphocytic leukemia cells but not with Notch activation

As previously reported, chronic lymphocytic leukemia (CLL) cells show constitutive Notch1/2 activation and express the Notchligand Jagged1. Despite increasing knowledge of the impact of Notch alterations on CLL biology and pathogenesis, the role of Jagged1 expressed in CLL cells remains undefined. I...

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Detalles Bibliográficos
Autores principales: De Falco, Filomena, Del Papa, Beatrice, Baldoni, Stefano, Sabatini, Rita, Falzetti, Franca, Di Ianni, Mauro, Martelli, Maria Paola, Mezzasoma, Federica, Pelullo, Maria, Marconi, Pierfrancesco, Sportoletti, Paolo, Screpanti, Isabella, Rosati, Emanuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255763/
https://www.ncbi.nlm.nih.gov/pubmed/30478302
http://dx.doi.org/10.1038/s41419-018-1185-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255763/
https://www.ncbi.nlm.nih.gov/pubmed/30478302
http://dx.doi.org/10.1038/s41419-018-1185-6

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