Cargando…

A biophysical study on the mechanism of interactions of DOX or PTX with α-lactalbumin as a delivery carrier

Doxorubicin and paclitaxel, two hydrophobic chemotherapeutic agents, are used in cancer therapies. Presence of hydrophobic patches and a flexible fold could probably make α-Lactalbumin a suitable carrier for hydrophobic drugs. In the present study, a variety of thermodynamic, spectroscopic, computat...

Descripción completa

Detalles Bibliográficos
Autores principales:	Delavari, Behdad, Mamashli, Fatemeh, Bigdeli, Bahareh, Poursoleiman, Atefeh, Karami, Leila, Zolmajd-Haghighi, Zahra, Ghasemi, Atiyeh, Samaei-Daryan, Samaneh, Hosseini, Morteza, Haertlé, Thomas, Muronetz, Vladimir I., Halskau, Øyvind, Moosavi-Movahedi, Ali Akbar, Goliaei, Bahram, Rezayan, Ali Hossein, Saboury, Ali Akbar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255783/ https://www.ncbi.nlm.nih.gov/pubmed/30478403 http://dx.doi.org/10.1038/s41598-018-35559-1

Ejemplares similares

Bivalent metal ions induce formation of α-synuclein fibril polymorphs with different cytotoxicities
por: Atarod, Deyhim, et al.
Publicado: (2022)

Modulation of cytotoxic amyloid fibrillation and mitochondrial damage of α-synuclein by catechols mediated conformational changes
por: Zohoorian-Abootorabi, Toktam, et al.
Publicado: (2023)

Amyloid management by chaperones: The mystery underlying protein oligomers’ dual functions
por: Arghavani, Payam, et al.
Publicado: (2022)

Curcumin Protects β-Lactoglobulin Fibril Formation and Fibril-Induced Neurotoxicity in PC12Cells
por: Mazaheri, Mansooreh, et al.
Publicado: (2015)

Hydrogel-Mediated DOX⋅HCl/PTX Delivery System for Breast Cancer Therapy
por: Hyun, Hoon, et al.
Publicado: (2019)

The calcium-free form of atorvastatin inhibits amyloid-β(1–42) aggregation in vitro
por: Nedaei, Hadi, et al.
Publicado: (2022)

Hydroxycinnamic Acid Derivatives from Coffee Extracts Prevent Amyloid Transformation of Alpha-Synuclein
por: Medvedeva, Maria, et al.
Publicado: (2022)

Inhibition of HEWL fibril formation by taxifolin: Mechanism of action
por: Mahdavimehr, Mohsen, et al.
Publicado: (2017)

Designing a new alginate-fibrinogen biomaterial composite hydrogel for wound healing
por: Soleimanpour, Marjan, et al.
Publicado: (2022)

Achilles' heel of the killer virus: the highly important molecular targets for hitting SARS-CoV-2 that causes COVID-19
por: Yousefi, Reza, et al.
Publicado: (2020)

Electrochemical Recognition of Metalloproteins by Bromide-modified Silver Electrode - A New Method
por: Rezaei-Zarchi, Saeed, et al.
Publicado: (2007)

New Insight on Biological Interaction Analysis: New Nanocrystalline Mixed Metal Oxide SPME Fiber for GC-FID Analysis of BTEX and Its Application in Human Hemoglobin-Benzene Interaction Studies
por: Hosseinzadeh, Reza, et al.
Publicado: (2014)

Computational investigation of inhibitory mechanism of flavonoids as bovine serum albumin anti-glycation agents
por: Johari, Anahita, et al.
Publicado: (2014)

Unraveling the novel effects of aroma from small molecules in preventing hen egg white lysozyme amyloid fibril formation
por: Seraj, Zahra, et al.
Publicado: (2018)

A health concern regarding the protein corona, aggregation and disaggregation
por: Falahati, Mojtaba, et al.
Publicado: (2019)

Current Developments in Native Nanometric Discoidal Membrane Bilayer Formed by Amphipathic Polymers
por: Esmaili, Mansoore, et al.
Publicado: (2021)

The Potential Role of Curcumin in Modulating the Master Antioxidant Pathway in Diabetic Hypoxia-Induced Complications
por: Ghareghomi, Somayyeh, et al.
Publicado: (2021)

Inhibitory Effects of Some Carbohydrates on Nano-Globular Aggregation of both Normal and Glycated Albumin
por: Moosavi-Movahedi, Ali Akbar, et al.
Publicado: (2016)

A tri state mechanism for oxygen release in fish hemoglobin: Using Barbus sharpeyi as a model
por: Dayer, Mohammad Reza, et al.
Publicado: (2014)

Review on oxidative stress relation on COVID-19: Biomolecular and bioanalytical approach
por: Ebrahimi, Mehrnaz, et al.
Publicado: (2021)

Characterization of insulin cross-seeding: the underlying mechanism reveals seeding and denaturant-induced insulin fibrillation proceeds through structurally similar intermediates
por: Akbarian, Mohsen, et al.
Publicado: (2020)

Unraveling the molecular heterogeneity in type 2 diabetes: a potential subtype discovery followed by metabolic modeling
por: Khoshnejat, Maryam, et al.
Publicado: (2020)

A holistic view of muscle metabolic reprogramming through personalized metabolic modeling in newly diagnosed diabetic patients
por: Khoshnejat, Maryam, et al.
Publicado: (2023)

Glycated albumin: an overview of the In Vitro models of an In Vivo potential disease marker
por: Arasteh, Amir, et al.
Publicado: (2014)

Correction: Thermal Unfolding Pathway of PHD2 Catalytic Domain in Three Different PHD2 Species: Computational Approaches
por: Hadi-Alijanvand, Hamid, et al.
Publicado: (2013)

Thermal Unfolding Pathway of PHD2 Catalytic Domain in Three Different PHD2 Species: Computational Approaches
por: Hadi-Alijanvand, Hamid, et al.
Publicado: (2012)

Personalizing the safe, appropriate and effective concentration(s) of ozone for a non-diabetic individual and four type II diabetic patients in autohemotherapy through blood hemoglobin analysis
por: Mehraban, Fouad, et al.
Publicado: (2019)

Determination of Diclofenac on a Dysprosium Nanowire- Modified Carbon Paste Electrode Accomplished in a Flow Injection System by Advanced Filtering
por: Daneshgar, Parandis, et al.
Publicado: (2009)

Prevention of haemoglobin glycation by acetylsalicylic acid (ASA): A new view on old mechanism
por: Ghazanfari-Sarabi, Shabnam, et al.
Publicado: (2019)

Nrf2 Modulation in Breast Cancer
por: Ghareghomi, Somayyeh, et al.
Publicado: (2022)

Amorphous aggregation of tau in the presence of titanium dioxide nanoparticles: biophysical, computational, and cellular studies
por: Fardanesh, Aida, et al.
Publicado: (2019)

Structural and functional studies of D109A human αB-crystallin contributing to the development of cataract and cardiomyopathy diseases
por: Hafizi, Mahtab, et al.
Publicado: (2021)

Role of Copper in the Onset of Alzheimer’s Disease Compared to Other Metals
por: Bagheri, Soghra, et al.
Publicado: (2018)

Oligomeric Forms of Insulin Amyloid Aggregation Disrupt Outgrowth and Complexity of Neuron-Like PC12 Cells
por: Kachooei, Ehsan, et al.
Publicado: (2012)

Kinetic data analysis of chaperone-like activity of Wt, R69C and D109H αB-crystallins
por: Ghahramani, Maryam, et al.
Publicado: (2019)

Computational Analysis of Reciprocal Association of Metabolism and Epigenetics in the Budding Yeast: A Genome-Scale Metabolic Model (GSMM) Approach
por: Salehzadeh-Yazdi, Ali, et al.
Publicado: (2014)

Applications for α-lactalbumin in human nutrition
por: Layman, Donald K, et al.
Publicado: (2018)

Functionalization of Alpha-Lactalbumin by Zinc Ions
por: Gołębiowski, Adrian, et al.
Publicado: (2022)

Glucose Oxidase Immobilized on a Functional Polymer Modified Glassy Carbon Electrode and Its Molecule Recognition of Glucose
por: Ning, Yan-Na, et al.
Publicado: (2019)

Advancing chirality analysis through enhanced enantiomer characterization and quantification via fast Fourier transform capacitance voltammetry
por: Ebrahimi, Mehrnaz, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_vgdrkj06l12rvmf1b1ghdgjptr