FOXO1 overexpression and loss of pSerine256-FOXO1 expression predicts clinical outcome in esophageal adenocarcinomas

The function of Forkhead box O 1 (FOXO1) and pSerine256-FOXO1 immunostaining in esophageal cancer is unclear. To clarify the prognostic role of nuclear FOXO1 and cytoplasmic pSerine256-FOXO1 immunostaining, a tissue microarray containing more than 600 esophageal cancers was analyzed. In non-neoplast...

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Detalles Bibliográficos
Autores principales: Grupp, Katharina, Uzunoglu, Faik Güntac, Melling, Nathaniel, Hofmann, Bianca, El Gammal, Alexander Tarek, Grotelüschen, Rainer, Heumann, Asmus, Bellon, Eugen, Reeh, Matthias, Wolters-Eisfeld, Gerrit, Ghabdan, Tarik, Nentwich, Michael, Bachmann, Kai, Bockhorn, Maximillian, Bogoevski, Dean, Izbicki, Jakob Robert, Kutup, Asad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255784/
https://www.ncbi.nlm.nih.gov/pubmed/30478420
http://dx.doi.org/10.1038/s41598-018-35459-4

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