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Clofazimine, but Not Isoniazid or Rifampicin, Augments Platelet Activation in vitro
Although the inclusion of the cationic amphiphilic, anti-mycobacterial agent, clofazimine, in the chemotherapeutic regimens of patients with multidrug-resistant tuberculosis (TB) has contributed to improved outcomes, concerns remain about the cardiotoxic potential of this agent. Accordingly, the cur...
Autores principales: | Anderson, Ronald, Theron, Annette J., Nel, Jan G., Durandt, Chrisna, Cholo, Moloko C., Feldman, Charles, Tintinger, Gregory R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255828/ https://www.ncbi.nlm.nih.gov/pubmed/30515097 http://dx.doi.org/10.3389/fphar.2018.01335 |
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