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Treatment outcome and associated factors among patients with epilepsy
Epilepsy is a major public health problem worldwide. Despite multiple drug therapies, people with epilepsy continue to have frequent seizures. There is a dearth of data on epilepsy treatment outcome and associated factors in our setting. Therefore, the aim of this was to assess treatment outcome and...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255833/ https://www.ncbi.nlm.nih.gov/pubmed/30478263 http://dx.doi.org/10.1038/s41598-018-35906-2 |
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author | Niriayo, Yirga Legesse Mamo, Abraham Kassa, Tesfaye Dessale Asgedom, Solomon Weldegebreal Atey, Tesfay Mahari Gidey, Kidu Demoz, Gebre Teklemariam Ibrahim, Seid |
author_facet | Niriayo, Yirga Legesse Mamo, Abraham Kassa, Tesfaye Dessale Asgedom, Solomon Weldegebreal Atey, Tesfay Mahari Gidey, Kidu Demoz, Gebre Teklemariam Ibrahim, Seid |
author_sort | Niriayo, Yirga Legesse |
collection | PubMed |
description | Epilepsy is a major public health problem worldwide. Despite multiple drug therapies, people with epilepsy continue to have frequent seizures. There is a dearth of data on epilepsy treatment outcome and associated factors in our setting. Therefore, the aim of this was to assess treatment outcome and associated factors among epileptic patients on follow up at the neurologic clinic of Ayder comprehensive specialized hospital, Ethiopia. A cross-sectional study was conducted on randomly selected epileptic patients. Data were collected through patient interview and review of medical records. Epilepsy treatment outcome was evaluated in terms of seizure control status in the last one year follow up period. Binary logistic regression analysis was performed to identify predictors of treatment outcome. A total of 270 patients were included. Of whom, 46.6% had controlled seizures. Whereas, 38.5%, 8.8%, and 5.9% had experienced seizure attacks 1–5 times, 6–10 times, and greater than 10 times, respectively. Alcohol consumption [adjusted odds ratio [(AOR): 14.87, 95% confidence interval (CI): 3.25–68.11], negative medication belief [AOR: 3.0, 95%CI: 1.31–6.71], low medication adherence [AOR:11.52, 95%CI: 3.25–40.82], and presence of comorbidities [AOR: 10.35, 95%CI: 4.40–24.40] were predictors of uncontrolled seizure. Our finding revealed that more than half of the epileptic patients had uncontrolled seizure. Epileptic patients with a negative medication belief, comorbidities, low medication adherence, and those who consume alcohol were more likely to have uncontrolled seizure. Therefore, more emphasis should be given to these patients. |
format | Online Article Text |
id | pubmed-6255833 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-62558332018-12-03 Treatment outcome and associated factors among patients with epilepsy Niriayo, Yirga Legesse Mamo, Abraham Kassa, Tesfaye Dessale Asgedom, Solomon Weldegebreal Atey, Tesfay Mahari Gidey, Kidu Demoz, Gebre Teklemariam Ibrahim, Seid Sci Rep Article Epilepsy is a major public health problem worldwide. Despite multiple drug therapies, people with epilepsy continue to have frequent seizures. There is a dearth of data on epilepsy treatment outcome and associated factors in our setting. Therefore, the aim of this was to assess treatment outcome and associated factors among epileptic patients on follow up at the neurologic clinic of Ayder comprehensive specialized hospital, Ethiopia. A cross-sectional study was conducted on randomly selected epileptic patients. Data were collected through patient interview and review of medical records. Epilepsy treatment outcome was evaluated in terms of seizure control status in the last one year follow up period. Binary logistic regression analysis was performed to identify predictors of treatment outcome. A total of 270 patients were included. Of whom, 46.6% had controlled seizures. Whereas, 38.5%, 8.8%, and 5.9% had experienced seizure attacks 1–5 times, 6–10 times, and greater than 10 times, respectively. Alcohol consumption [adjusted odds ratio [(AOR): 14.87, 95% confidence interval (CI): 3.25–68.11], negative medication belief [AOR: 3.0, 95%CI: 1.31–6.71], low medication adherence [AOR:11.52, 95%CI: 3.25–40.82], and presence of comorbidities [AOR: 10.35, 95%CI: 4.40–24.40] were predictors of uncontrolled seizure. Our finding revealed that more than half of the epileptic patients had uncontrolled seizure. Epileptic patients with a negative medication belief, comorbidities, low medication adherence, and those who consume alcohol were more likely to have uncontrolled seizure. Therefore, more emphasis should be given to these patients. Nature Publishing Group UK 2018-11-26 /pmc/articles/PMC6255833/ /pubmed/30478263 http://dx.doi.org/10.1038/s41598-018-35906-2 Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Niriayo, Yirga Legesse Mamo, Abraham Kassa, Tesfaye Dessale Asgedom, Solomon Weldegebreal Atey, Tesfay Mahari Gidey, Kidu Demoz, Gebre Teklemariam Ibrahim, Seid Treatment outcome and associated factors among patients with epilepsy |
title | Treatment outcome and associated factors among patients with epilepsy |
title_full | Treatment outcome and associated factors among patients with epilepsy |
title_fullStr | Treatment outcome and associated factors among patients with epilepsy |
title_full_unstemmed | Treatment outcome and associated factors among patients with epilepsy |
title_short | Treatment outcome and associated factors among patients with epilepsy |
title_sort | treatment outcome and associated factors among patients with epilepsy |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6255833/ https://www.ncbi.nlm.nih.gov/pubmed/30478263 http://dx.doi.org/10.1038/s41598-018-35906-2 |
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